Selective actin-binding is the most prominent biochemical property of the scarce marine natural product latrunculin A (see formula). Modern metal-catalyzed C-C bond-formation reactions, including a ring-closing enyne–yne metathesis (shown in red), now open a convenient, flexible, and productive entry to this important probe molecule for chemical biology
International audienceThe synthesis of the C1–C27 fragment of hemicalide, a marine metabolite displa...
A highly efficient entry into the resin glycoside family of natural products is outlined which takes...
textThe application of ring-closing enyne metathesis (RCEYM) reactions to the preparation of biolog...
Selective actin-binding is the most prominent biochemical property of the scarce marine natural prod...
The highly selective actin-binding latrunculins (e.g. 1) play a prominent role as probe molecules in...
The latrunculins are highly selective actin-binding marine natural products and as such play an impo...
Two largely catalysis-based and highly convergent total syntheses of latrunculin A (1) and B (2) wer...
Deliberate digression from the blueprint of the total syntheses of latrunculin A (1) and latrunculin...
International audienceLatrunculins are marine toxins used in cell biology to block actin polymerizat...
A comparative investigation shows that hydroxylated 10-membered lactones modeled around the fungal m...
The evolution of an enantioselective total synthesis of (+)-18-<i>epi</i>-latrunculol A, a congener ...
The total synthesis of (+)-18-epi-latrunculol A was undertaken to provide synthetic access to a suff...
Development of a unified strategy for the total synthesis of the enmein-type ent-Kauranoids is discl...
Latrunculins are unique macrolides containing a thiazolidinone moiety. Latrunculin A (<b>1</b>), lat...
| openaire: EC/FP7/316149/EU//INNOVABALTCalyculins are a class of highly cytotoxic metabolites origi...
International audienceThe synthesis of the C1–C27 fragment of hemicalide, a marine metabolite displa...
A highly efficient entry into the resin glycoside family of natural products is outlined which takes...
textThe application of ring-closing enyne metathesis (RCEYM) reactions to the preparation of biolog...
Selective actin-binding is the most prominent biochemical property of the scarce marine natural prod...
The highly selective actin-binding latrunculins (e.g. 1) play a prominent role as probe molecules in...
The latrunculins are highly selective actin-binding marine natural products and as such play an impo...
Two largely catalysis-based and highly convergent total syntheses of latrunculin A (1) and B (2) wer...
Deliberate digression from the blueprint of the total syntheses of latrunculin A (1) and latrunculin...
International audienceLatrunculins are marine toxins used in cell biology to block actin polymerizat...
A comparative investigation shows that hydroxylated 10-membered lactones modeled around the fungal m...
The evolution of an enantioselective total synthesis of (+)-18-<i>epi</i>-latrunculol A, a congener ...
The total synthesis of (+)-18-epi-latrunculol A was undertaken to provide synthetic access to a suff...
Development of a unified strategy for the total synthesis of the enmein-type ent-Kauranoids is discl...
Latrunculins are unique macrolides containing a thiazolidinone moiety. Latrunculin A (<b>1</b>), lat...
| openaire: EC/FP7/316149/EU//INNOVABALTCalyculins are a class of highly cytotoxic metabolites origi...
International audienceThe synthesis of the C1–C27 fragment of hemicalide, a marine metabolite displa...
A highly efficient entry into the resin glycoside family of natural products is outlined which takes...
textThe application of ring-closing enyne metathesis (RCEYM) reactions to the preparation of biolog...
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