The oral mucosa consists of diverse and understudied epithelia that all exhibit remarkable capacity for repair. It is thought that reserve populations of stem cells are responsible for replenishing epithelia following injury, though no markers for reserve stem cells have been identified in the oral epithelia. Previous studies in epithelial tissues such as the epidermis and intestine have found that regenerative stem-like cell populations generally reside in the basal layer of these stratified epithelia. Here, we seek to identify candidate reserve stem cells through an unbiased genetic “pulse-chase” strategy.Bachelor of Scienc
Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal e...
Purpose: Currently, there are no definitive immunomarkers for epithelial stem cells (corneal and con...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent ‘‘label retai...
Stem cells in stratified epithelia are generally believed to adhere to a non-hierarchical single-pro...
BACKGROUND & AIMS: Intestinal homeostasis and regeneration after injury are controlled by 2 differen...
A subpopulation of basal epithelial cells which retains tritiated thymidine label for extended perio...
Objective The identification of stem cells (SC) remains challenging. In the human oral mucosal epith...
Reserve intestinal stem cells (rISCs) are quiescent/slowly cycling under homeostatic conditions, all...
SummarySkin epithelia must rejuvenate constantly during normal homeostasis and repair damage after w...
The inability to identify, isolate, and culture intestinal epithelial stem cells (IESCs) has been pr...
Homeostasis of continuously renewing tissues, such as the epidermis, is maintained by somatic undiff...
Epithelia cover the surfaces and line the cavities of the body. Recent studies have highlighted the ...
The identification and characterization of stem cells is a major focus of developmental biology and ...
Xerostomia or dry mouth is a hyposalivation condition that leads to difficulty in speaking, eating, ...
It is generally important to elucidate airway epithelial cell lineages and to identify multipotent p...
Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal e...
Purpose: Currently, there are no definitive immunomarkers for epithelial stem cells (corneal and con...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent ‘‘label retai...
Stem cells in stratified epithelia are generally believed to adhere to a non-hierarchical single-pro...
BACKGROUND & AIMS: Intestinal homeostasis and regeneration after injury are controlled by 2 differen...
A subpopulation of basal epithelial cells which retains tritiated thymidine label for extended perio...
Objective The identification of stem cells (SC) remains challenging. In the human oral mucosal epith...
Reserve intestinal stem cells (rISCs) are quiescent/slowly cycling under homeostatic conditions, all...
SummarySkin epithelia must rejuvenate constantly during normal homeostasis and repair damage after w...
The inability to identify, isolate, and culture intestinal epithelial stem cells (IESCs) has been pr...
Homeostasis of continuously renewing tissues, such as the epidermis, is maintained by somatic undiff...
Epithelia cover the surfaces and line the cavities of the body. Recent studies have highlighted the ...
The identification and characterization of stem cells is a major focus of developmental biology and ...
Xerostomia or dry mouth is a hyposalivation condition that leads to difficulty in speaking, eating, ...
It is generally important to elucidate airway epithelial cell lineages and to identify multipotent p...
Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal e...
Purpose: Currently, there are no definitive immunomarkers for epithelial stem cells (corneal and con...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent ‘‘label retai...