The Effects of Exercise Intensity by the Type of Gene Mutation of Obese Women on Changes in Leptin, Insulin and LDH-CPK

Subjects selected for this study were obese middle-aged women aged between 35 and 45 with a BMI of 25 to 30. The subjects were divided into three groups; obese group with no influence of gene mutation, β3 adrenergic receptor gene mutation group and group with two kinds of gene mutations including β3 adrenergic receptor (β3-Ar) and PPAR-γ. This study conducted the treadmill walking test on each group at 40~50% HR max???50~60% HR max and 60~70% HR max about 80 minutes respectively, using a Latin Square design in order to examine the changes in Leptin, Insulin and Plasma LDH & CPK, intending to establish the optimal exercise intensity by cause according to gene type of obesity. The main results of this study were as follow: The Leptin, Insulin, LDH, CPK level showed significant differences in exercise period (p???.001), and also in interaction between exercise period and group (p???.01). The regardless of types and existence of genes and variation of strength of exercise, the walking which is representative of aerobic exercise can solve and protect the obesity