AbstractAdeno-associated virus type 2 nonstructural protein Rep78 [621 amino acids (aa) long] affects the expression of various cellular and viral genes. In this study we examined the effects of Rep78 on expression of the luciferase gene from the human cytomegalovirus immediate-early promoter in HeLa cells and on translation of RNA encoding luciferase in rabbit reticulocyte lysate. When Rep78 and luciferase were coexpressed, the luciferase activity decreased despite increased levels of luciferase mRNA in the cells. Purified Rep78 or Rep68 fused with Escherichia coli maltose binding protein suppressed translation of luciferase RNA in vitro, but Rep52/40 fusion proteins did not. A mutated Rep78, which is 520 aa long and truncated at its C-ter...
inhibition of primary human cells. progeny virions: Rep-mediated growth Rep proteins in wild-type an...
AbstractAdeno-associated virus (AAV) replication proteins Rep78 and Rep68 play major roles in the li...
The adeno-associated virus type 2 (AAV) replication (Rep) proteins Rep78 and 68 (Rep78/68) exhibit a...
AbstractAdeno-associated virus (AAV) replication (Rep) proteins are pleiotropic effectors of viral D...
AbstractThe Rep68 and Rep78 proteins of adeno-associated virus type-2 (AAV) are multifunctional DNA ...
The adeno-associated virus (AAV) rep gene encodes four proteins (Rep78, Rep68, Rep52, and Rep4O) req...
Abstract]he large rep gene products, Rep78 and Rep68, of adeno-associated virus (AAV) are pleiotropi...
AbstractThe adeno-associated virus (AAV) replication proteins Rep78 and Rep68 regulate viral gene ex...
AbstractRep78/68 proteins of adeno-associated virus type 2 (AAV-2) are involved in many aspects of t...
The Rep68 and Rep78 proteins (Rep68/78) of adeno-associated virus type 2 (AAV) are critical for AAV ...
AbstractThe large Rep proteins Rep78 and Rep68 of the helper-dependent adeno associated virus type 2...
rep-negative AAV mutant. sufficient for infectious-particle formation by a virus (AAV) Rep78 or Rep6...
AbstractRep78 is the major regulatory protein of adenoassociated virus (AAV). Rep78 is able to trans...
The adeno-associated virus type 2 (AAV) large Rep proteins can act to increase the ratio of spliced ...
AbstractThrough yeast two-hybrid analysis and coimmunoprecipitation studies, we have identified a no...
inhibition of primary human cells. progeny virions: Rep-mediated growth Rep proteins in wild-type an...
AbstractAdeno-associated virus (AAV) replication proteins Rep78 and Rep68 play major roles in the li...
The adeno-associated virus type 2 (AAV) replication (Rep) proteins Rep78 and 68 (Rep78/68) exhibit a...
AbstractAdeno-associated virus (AAV) replication (Rep) proteins are pleiotropic effectors of viral D...
AbstractThe Rep68 and Rep78 proteins of adeno-associated virus type-2 (AAV) are multifunctional DNA ...
The adeno-associated virus (AAV) rep gene encodes four proteins (Rep78, Rep68, Rep52, and Rep4O) req...
Abstract]he large rep gene products, Rep78 and Rep68, of adeno-associated virus (AAV) are pleiotropi...
AbstractThe adeno-associated virus (AAV) replication proteins Rep78 and Rep68 regulate viral gene ex...
AbstractRep78/68 proteins of adeno-associated virus type 2 (AAV-2) are involved in many aspects of t...
The Rep68 and Rep78 proteins (Rep68/78) of adeno-associated virus type 2 (AAV) are critical for AAV ...
AbstractThe large Rep proteins Rep78 and Rep68 of the helper-dependent adeno associated virus type 2...
rep-negative AAV mutant. sufficient for infectious-particle formation by a virus (AAV) Rep78 or Rep6...
AbstractRep78 is the major regulatory protein of adenoassociated virus (AAV). Rep78 is able to trans...
The adeno-associated virus type 2 (AAV) large Rep proteins can act to increase the ratio of spliced ...
AbstractThrough yeast two-hybrid analysis and coimmunoprecipitation studies, we have identified a no...
inhibition of primary human cells. progeny virions: Rep-mediated growth Rep proteins in wild-type an...
AbstractAdeno-associated virus (AAV) replication proteins Rep78 and Rep68 play major roles in the li...
The adeno-associated virus type 2 (AAV) replication (Rep) proteins Rep78 and 68 (Rep78/68) exhibit a...