AbstractIn this issue of Cancer Cell, Gidekel et al. demonstrate that Oct-4, a member of the POU class of homeobox genes, is a critical player in the genesis of testicular germ cell tumors. This study provides further evidence that deregulated expression of homeobox genes, which occurs in many solid tumors, is functionally relevant for carcinogenesis and highlights unique features that distinguish homeobox genes from other cancer-promoting genes
The Oct3/4 gene, a POU family transcription factor, has been noted as being specifically expressed i...
Introduction: Cancer stem cells are a small subpopulation of cells within a tumor which are responsi...
The Hox gene family plays an important role in organogenesis and animal development. Currently, 39 H...
AbstractIn this issue of Cancer Cell, Gidekel et al. demonstrate that Oct-4, a member of the POU cla...
The homeobox (HOX) genes encoding an evolutionarily highly conserved family of homeodomain-containin...
It is widely accepted that many of the molecular pathways that underlie carcinogenesis represent abe...
The transformation of a cell and the acquisition of the invasive and metastatic phenotype result fro...
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, and is the third leading cau...
Copyright: © 2014 Procino A. This is an open-access article distributed under the terms of the Crea...
Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily genes, play piv...
Genito-urinary malignancies (prostate, bladder, renal and testicular cancers) rank high among human ...
AbstractThe Oct-3/4 transcription factor sustains embryonic stem (ES) cell self-renewal and is a dos...
Homeobox (HOX) genes encode highly conserved homeotic transcription factors that play a crucial role...
Abstract Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily genes...
Homeobox genes encode DNA-binding proteins that regulate gene expression during embryonic developmen...
The Oct3/4 gene, a POU family transcription factor, has been noted as being specifically expressed i...
Introduction: Cancer stem cells are a small subpopulation of cells within a tumor which are responsi...
The Hox gene family plays an important role in organogenesis and animal development. Currently, 39 H...
AbstractIn this issue of Cancer Cell, Gidekel et al. demonstrate that Oct-4, a member of the POU cla...
The homeobox (HOX) genes encoding an evolutionarily highly conserved family of homeodomain-containin...
It is widely accepted that many of the molecular pathways that underlie carcinogenesis represent abe...
The transformation of a cell and the acquisition of the invasive and metastatic phenotype result fro...
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, and is the third leading cau...
Copyright: © 2014 Procino A. This is an open-access article distributed under the terms of the Crea...
Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily genes, play piv...
Genito-urinary malignancies (prostate, bladder, renal and testicular cancers) rank high among human ...
AbstractThe Oct-3/4 transcription factor sustains embryonic stem (ES) cell self-renewal and is a dos...
Homeobox (HOX) genes encode highly conserved homeotic transcription factors that play a crucial role...
Abstract Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily genes...
Homeobox genes encode DNA-binding proteins that regulate gene expression during embryonic developmen...
The Oct3/4 gene, a POU family transcription factor, has been noted as being specifically expressed i...
Introduction: Cancer stem cells are a small subpopulation of cells within a tumor which are responsi...
The Hox gene family plays an important role in organogenesis and animal development. Currently, 39 H...