Two new papers (Kuranaga et al., 2006; Oshima et al., 2006) describe a previously uncharacterized Drosophila kinase (DmIKKɛ) that regulates the abundance of DIAP1, a protein best known for its ability to inhibit apoptosis. However, DmIKKɛ-mediated degradation of DIAP1 does not regulate apoptosis as might be predicted but instead regulates actin dynamics, cell morphology, and the differentiation of sensory organ precursor cells
<p>The <i>Drosophila</i> caspase Dronc, which is required for fly development, is composed of an N-t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...
In the present study, we report that ubiquitin-mediated degradation of dMyc, the Drosophila homologu...
Two new papers (Kuranaga et al., 2006; Oshima et al., 2006) describe a previously uncharacterized Dr...
SummaryCaspase activation has been extensively studied in the context of apoptosis. However, caspase...
Apoptosis is an evolutionarily conserved, actively regulated cell death process that plays an essent...
Inhibitor of apoptosis proteins (IAPs) act as endogenous inhibitors of active caspases. Drosophila I...
Although loss of the inhibitor of apoptosis (LAP) protein DIAP1 has been shown to result in caspase ...
SummaryDifferentiated cells assume complex shapes through polarized cell migration and growth. These...
AbstractThe proper number of cells in developing tissues is achieved by coordinating cell division w...
It is becoming clear that "apoptotic" caspases can effect cellular processes other than cell death. ...
AbstractIt is becoming clear that “apoptotic” caspases can effect cellular processes other than cell...
Faculty Mentor: Pascal Meier Programmed cell death, known as “apoptosis,” is an essential part of de...
The Drosophila extracellular signal-regulated kinase (DERK) mitogen-activated protein kinase (MAPK) ...
Caspases provide vital links in non-apoptotic regulatory networks controlling inflammation, compensa...
<p>The <i>Drosophila</i> caspase Dronc, which is required for fly development, is composed of an N-t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...
In the present study, we report that ubiquitin-mediated degradation of dMyc, the Drosophila homologu...
Two new papers (Kuranaga et al., 2006; Oshima et al., 2006) describe a previously uncharacterized Dr...
SummaryCaspase activation has been extensively studied in the context of apoptosis. However, caspase...
Apoptosis is an evolutionarily conserved, actively regulated cell death process that plays an essent...
Inhibitor of apoptosis proteins (IAPs) act as endogenous inhibitors of active caspases. Drosophila I...
Although loss of the inhibitor of apoptosis (LAP) protein DIAP1 has been shown to result in caspase ...
SummaryDifferentiated cells assume complex shapes through polarized cell migration and growth. These...
AbstractThe proper number of cells in developing tissues is achieved by coordinating cell division w...
It is becoming clear that "apoptotic" caspases can effect cellular processes other than cell death. ...
AbstractIt is becoming clear that “apoptotic” caspases can effect cellular processes other than cell...
Faculty Mentor: Pascal Meier Programmed cell death, known as “apoptosis,” is an essential part of de...
The Drosophila extracellular signal-regulated kinase (DERK) mitogen-activated protein kinase (MAPK) ...
Caspases provide vital links in non-apoptotic regulatory networks controlling inflammation, compensa...
<p>The <i>Drosophila</i> caspase Dronc, which is required for fly development, is composed of an N-t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...
In the present study, we report that ubiquitin-mediated degradation of dMyc, the Drosophila homologu...
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