During axon specification, growth promoting proteins localize selectively to the growing axon. In this issue of Neuron, Cheng et al. report how selective protein degradation, controlled by a substrate switch of the ubiquitin ligase Smurf1, specifies Par6 and RhoA localization and thereby regulates neuronal polarity
AbstractThe Rho-family of small GTPases consists of essential regulators of neurite outgrowth, axona...
Although neuronal functions depend on their robust polarity, the mechanisms that ensure generation a...
SummaryThe degeneration of axons is the underlying pathological process of several neurological diso...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
SummaryUbiquitin E3 ligases serve for ubiquitination of specific substrates, and its ligase efficacy...
SummaryUbiquitin E3 ligases serve for ubiquitination of specific substrates, and its ligase efficacy...
SummaryPlanar cell polarity (PCP) is critical for morphogenesis in metazoans. PCP in vertebrates reg...
[[sponsorship]]分子生物研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...
<p>The E3 ubiquitin ligase Cdh1-APC operates upstream of the RhoA-regulating proteins Smurf1 and p25...
Neuronal polarization requires coordinated regulation of membrane trafficking and cytoskeletal dynam...
The assembly of functional neuronal networks in the developing animal relies on the polarization of ...
The assembly of functional neuronal networks in the developing animal relies on the polarization of ...
AbstractThe Rho-family of small GTPases consists of essential regulators of neurite outgrowth, axona...
Although neuronal functions depend on their robust polarity, the mechanisms that ensure generation a...
SummaryThe degeneration of axons is the underlying pathological process of several neurological diso...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
During axon specification, growth promoting proteins localize selectively to the growing axon. In th...
SummaryUbiquitin E3 ligases serve for ubiquitination of specific substrates, and its ligase efficacy...
SummaryUbiquitin E3 ligases serve for ubiquitination of specific substrates, and its ligase efficacy...
SummaryPlanar cell polarity (PCP) is critical for morphogenesis in metazoans. PCP in vertebrates reg...
[[sponsorship]]分子生物研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...
<p>The E3 ubiquitin ligase Cdh1-APC operates upstream of the RhoA-regulating proteins Smurf1 and p25...
Neuronal polarization requires coordinated regulation of membrane trafficking and cytoskeletal dynam...
The assembly of functional neuronal networks in the developing animal relies on the polarization of ...
The assembly of functional neuronal networks in the developing animal relies on the polarization of ...
AbstractThe Rho-family of small GTPases consists of essential regulators of neurite outgrowth, axona...
Although neuronal functions depend on their robust polarity, the mechanisms that ensure generation a...
SummaryThe degeneration of axons is the underlying pathological process of several neurological diso...