BCL6 is a zinc-finger transcriptional repressor known for its oncogenic role in B cell lymphoma. In a recent issue of Nature, Duy et al. describe a novel role for BCL6 at the center of a transcriptional network in Ph+ acute lymphoblastic leukemia cells that modulates their leukemogenicity and response to kinase inhibitors
Philadelphia chromosome–positive acute lymphoblastic leukemia (Phþ ALL) is currently treated with BC...
Review on BCL6 (B-Cell Lymphoma 6), with data on DNA, on the protein encoded, and where the gene is ...
Primary mediastinal B cell lymphoma (PMBL) is characterized by specific molecular hallmarks includin...
B cell lymphoma 6 (Bcl6) is a proto-oncogene functioning as a transcriptional repressor at the germi...
Inappropriate expression or activation of transcription factors can drive patterns of gene expressio...
Chromosomal rearrangements of the mixed lineage leukemia (MLL) gene occur in ∼10% of B-cell acute ly...
The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhi...
The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhi...
B-cell Lymphoma 6 (BCL6) and its close homolog BCL6B encode proteins that are members of the BTB-Zin...
The bone marrow niche has a significant impact on acute lymphoblastic leukemia (ALL) cell phenotype....
The bone marrow niche has a significant impact on acute lymphoblastic leukemia (ALL) cell phenotype....
Transcription factors have proven to be difficult targets for the development of small-molecule drug...
B-cell Lymphoma 6 (BCL6) and its close homolog BCL6B encode proteins that are members of the BTB-Zin...
International audienceThe B-cell lymphoma 6 (BCL6) gene encodes a transcriptional repressor containi...
Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) is currently treated with BCR...
Philadelphia chromosome–positive acute lymphoblastic leukemia (Phþ ALL) is currently treated with BC...
Review on BCL6 (B-Cell Lymphoma 6), with data on DNA, on the protein encoded, and where the gene is ...
Primary mediastinal B cell lymphoma (PMBL) is characterized by specific molecular hallmarks includin...
B cell lymphoma 6 (Bcl6) is a proto-oncogene functioning as a transcriptional repressor at the germi...
Inappropriate expression or activation of transcription factors can drive patterns of gene expressio...
Chromosomal rearrangements of the mixed lineage leukemia (MLL) gene occur in ∼10% of B-cell acute ly...
The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhi...
The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhi...
B-cell Lymphoma 6 (BCL6) and its close homolog BCL6B encode proteins that are members of the BTB-Zin...
The bone marrow niche has a significant impact on acute lymphoblastic leukemia (ALL) cell phenotype....
The bone marrow niche has a significant impact on acute lymphoblastic leukemia (ALL) cell phenotype....
Transcription factors have proven to be difficult targets for the development of small-molecule drug...
B-cell Lymphoma 6 (BCL6) and its close homolog BCL6B encode proteins that are members of the BTB-Zin...
International audienceThe B-cell lymphoma 6 (BCL6) gene encodes a transcriptional repressor containi...
Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) is currently treated with BCR...
Philadelphia chromosome–positive acute lymphoblastic leukemia (Phþ ALL) is currently treated with BC...
Review on BCL6 (B-Cell Lymphoma 6), with data on DNA, on the protein encoded, and where the gene is ...
Primary mediastinal B cell lymphoma (PMBL) is characterized by specific molecular hallmarks includin...
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