The molecular mechanisms that integrate cellular polarity with tissue architecture during epithelial morphogenesis are poorly understood. Using a three-dimensional model of epithelial morphogenesis, Martin-Belmonte et al. (2007) report that the phosphatase PTEN and phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2] regulate the GTPase Cdc42 and the kinase aPKC to generate the apical plasma membrane domain and maintain apical-basolateral polarity
The establishment andmaintenance of cell polarity is important to awide range of biological processe...
SummaryThe formation of epithelial tissues containing lumens requires not only the apical-basolatera...
Breaking of cellular symmetry in order to establish an apico-basal polarity axis initiates de novo f...
The molecular mechanisms that integrate cellular polarity with tissue architecture during epithelial...
Epithelial cells sense their surrounding environment via mechanical and chemical stimuli, responding...
International audienceBACKGROUND: The control of apical-basal polarity in epithelial layers is a fun...
Polarized epithelial cells have a distinctive apical–basal axis of polarity for vectorial transport ...
Inositol phospholipids have been implicated in almost all aspects of cellular physiology including s...
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains...
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains...
During embryonic development, columnar epithelial cells polarize their plasma membrane into distinct...
Epithelial cells are polarized cells and typically display distinct plasma membrane domains: basal p...
Plasma membranes of epithelial cells consist of two domains, an apical and a basolateral domain, the...
AbstractHow epithelial cells subdivide their plasma membrane into an apical and a basolateral domain...
SummaryBackgroundIn a specialized epithelial cell such as the Drosophila photoreceptor, a conserved ...
The establishment andmaintenance of cell polarity is important to awide range of biological processe...
SummaryThe formation of epithelial tissues containing lumens requires not only the apical-basolatera...
Breaking of cellular symmetry in order to establish an apico-basal polarity axis initiates de novo f...
The molecular mechanisms that integrate cellular polarity with tissue architecture during epithelial...
Epithelial cells sense their surrounding environment via mechanical and chemical stimuli, responding...
International audienceBACKGROUND: The control of apical-basal polarity in epithelial layers is a fun...
Polarized epithelial cells have a distinctive apical–basal axis of polarity for vectorial transport ...
Inositol phospholipids have been implicated in almost all aspects of cellular physiology including s...
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains...
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains...
During embryonic development, columnar epithelial cells polarize their plasma membrane into distinct...
Epithelial cells are polarized cells and typically display distinct plasma membrane domains: basal p...
Plasma membranes of epithelial cells consist of two domains, an apical and a basolateral domain, the...
AbstractHow epithelial cells subdivide their plasma membrane into an apical and a basolateral domain...
SummaryBackgroundIn a specialized epithelial cell such as the Drosophila photoreceptor, a conserved ...
The establishment andmaintenance of cell polarity is important to awide range of biological processe...
SummaryThe formation of epithelial tissues containing lumens requires not only the apical-basolatera...
Breaking of cellular symmetry in order to establish an apico-basal polarity axis initiates de novo f...