ObjectivesThis study was designed to determine whether alternate pro-B-type natriuretic peptide (proBNP) and BNP forms circulate in the general population.BackgroundBioactive BNP1-32and NT-proBNP1-76are derived from a precursor molecule, proBNP1-108. Recent data suggest that aminodipeptidase-processed forms of BNP1-32(BNP3-32) and of proBNP1-108itself (proBNP3-108) may circulate and have additional diagnostic potential.MethodsResidents (age ≥45 years) of Olmsted County, Minnesota, underwent medical review, echocardiography, and phlebotomy for 2 novel assays specific for proBNP3-108and BNP3-32and 2 commercial assays (Triage BNP and Roche NT-proBNP). Groups included normal subjects (n = 613), cardiovascular disease with normal ventricular fun...
Background—B-type natriuretic peptide (BNP) is produced as a biologically inactive prohormone (proBN...
The measurement of the active hormone of B-type natriuretic peptide (BNP) system actually has severa...
Background—Multiple B-type natriuretic peptide (BNP) fragments circulate in patients with heart fail...
ObjectivesThis study was designed to determine whether alternate pro-B-type natriuretic peptide (pro...
ObjectivesThese studies describe molecular forms of circulating B-type natriuretic peptide (BNP) as ...
Discovery of the endocrine function of the heart, which exerts a fundamental role in regulating card...
peptide (BNP) precursor (proBNP), BNP, and the N-terminal fragment of proBNP (NT-proBNP) are used as...
OBJECTIVES: B-type natriuretic peptide (BNP) and amino-terminal proBNP (Nt-proBNP) are derived from ...
ObjectivesThe purpose of this study was to investigate circulating pro–B-type natriuretic peptide (p...
Background: Measurement of B-type natriuretic peptide (BNP) concentration or its precursor (N-termin...
Both biologically active BNP1-32 and inactive NT-proBNP1-76 are released in circulation from prohorm...
Background: Brain natriuretic peptides are relevant markers of heart impairment. Aim: We investigate...
The thesis evaluated the role of the B-type natriuretic peptides and N-terminal pro-B-type natriuret...
B-type natriuretic peptide (BNP), a clinical biomarker for cardiovascular disease (CVD), is secreted...
Free to read BACKGROUND: The use of nonstandardized N-terminal pro-B-type natriuretic peptide (NT-pr...
Background—B-type natriuretic peptide (BNP) is produced as a biologically inactive prohormone (proBN...
The measurement of the active hormone of B-type natriuretic peptide (BNP) system actually has severa...
Background—Multiple B-type natriuretic peptide (BNP) fragments circulate in patients with heart fail...
ObjectivesThis study was designed to determine whether alternate pro-B-type natriuretic peptide (pro...
ObjectivesThese studies describe molecular forms of circulating B-type natriuretic peptide (BNP) as ...
Discovery of the endocrine function of the heart, which exerts a fundamental role in regulating card...
peptide (BNP) precursor (proBNP), BNP, and the N-terminal fragment of proBNP (NT-proBNP) are used as...
OBJECTIVES: B-type natriuretic peptide (BNP) and amino-terminal proBNP (Nt-proBNP) are derived from ...
ObjectivesThe purpose of this study was to investigate circulating pro–B-type natriuretic peptide (p...
Background: Measurement of B-type natriuretic peptide (BNP) concentration or its precursor (N-termin...
Both biologically active BNP1-32 and inactive NT-proBNP1-76 are released in circulation from prohorm...
Background: Brain natriuretic peptides are relevant markers of heart impairment. Aim: We investigate...
The thesis evaluated the role of the B-type natriuretic peptides and N-terminal pro-B-type natriuret...
B-type natriuretic peptide (BNP), a clinical biomarker for cardiovascular disease (CVD), is secreted...
Free to read BACKGROUND: The use of nonstandardized N-terminal pro-B-type natriuretic peptide (NT-pr...
Background—B-type natriuretic peptide (BNP) is produced as a biologically inactive prohormone (proBN...
The measurement of the active hormone of B-type natriuretic peptide (BNP) system actually has severa...
Background—Multiple B-type natriuretic peptide (BNP) fragments circulate in patients with heart fail...