AbstractCyclic AMP (cAMP) is one of the intracellular messengers that mediate odorant signal transduction in vertebrate olfactory cilia. Therefore, the diffusion coefficient of cAMP in olfactory cilia is an important factor in the transduction of the odorous signal. We have employed the excised cilium preparation from the grass frog (Rana pipiens) to measure the cAMP diffusion coefficient. In this preparation an olfactory cilium is drawn into a patch pipette and a gigaseal is formed at the base of the cilium. Subsequently the cilium is excised, allowing bath cAMP to diffuse into the cilium and activate the cyclic nucleotide-gated channels on the plasma membrane. In order to estimate the cAMP diffusion coefficient, we analyzed the kinetics o...
ABSTRACTThe basal conductance of unstimulated frog olfactory receptor neurons was investigated using...
It has previously been proposed that a Ca2+-dependent K + conductance is implicated in the inhibitor...
Olfactory sensory neurons respond to odorants increasing Ca2+ concentrations in their chemosensory c...
AbstractCyclic AMP (cAMP) is one of the intracellular messengers that mediate odorant signal transdu...
AbstractOlfactory cilia contain the known components of olfactory signal transduction, including a h...
Although cAMP is well established as a second messenger for olfactory transduction in vertebrates, t...
In vertebrate olfactory receptor neurons, sensory cilia transduce odor stimuli into changes in neuro...
Signal transduction depends critically on the spatial localization of protein constituents. A key qu...
Odor stimulation may excite or inhibit olfactory receptor neurons (ORNs). It is well established tha...
Most vertebrate olfactory receptor neurons share a common G-protein–coupled pathway for transducing ...
Background: In any fine sensory organelle, a small influx of Ca2+ can quickly elevate cytoplasmic Ca...
The initial steps of olfaction occur in primary sensory neurons located in the olfactory epithelium ...
Electron microscopic examination of intact olfactory epithelia in different animals yielded the same...
AbstractPatch clamp technique was used to record cyclic nucleotide-dependent current of the frog olf...
The diffusion coefficient of fluorescein in detached cilia of Xenopus laevis olfactory receptor neur...
ABSTRACTThe basal conductance of unstimulated frog olfactory receptor neurons was investigated using...
It has previously been proposed that a Ca2+-dependent K + conductance is implicated in the inhibitor...
Olfactory sensory neurons respond to odorants increasing Ca2+ concentrations in their chemosensory c...
AbstractCyclic AMP (cAMP) is one of the intracellular messengers that mediate odorant signal transdu...
AbstractOlfactory cilia contain the known components of olfactory signal transduction, including a h...
Although cAMP is well established as a second messenger for olfactory transduction in vertebrates, t...
In vertebrate olfactory receptor neurons, sensory cilia transduce odor stimuli into changes in neuro...
Signal transduction depends critically on the spatial localization of protein constituents. A key qu...
Odor stimulation may excite or inhibit olfactory receptor neurons (ORNs). It is well established tha...
Most vertebrate olfactory receptor neurons share a common G-protein–coupled pathway for transducing ...
Background: In any fine sensory organelle, a small influx of Ca2+ can quickly elevate cytoplasmic Ca...
The initial steps of olfaction occur in primary sensory neurons located in the olfactory epithelium ...
Electron microscopic examination of intact olfactory epithelia in different animals yielded the same...
AbstractPatch clamp technique was used to record cyclic nucleotide-dependent current of the frog olf...
The diffusion coefficient of fluorescein in detached cilia of Xenopus laevis olfactory receptor neur...
ABSTRACTThe basal conductance of unstimulated frog olfactory receptor neurons was investigated using...
It has previously been proposed that a Ca2+-dependent K + conductance is implicated in the inhibitor...
Olfactory sensory neurons respond to odorants increasing Ca2+ concentrations in their chemosensory c...