Coexistence of Pernicious Anemia and Myasthenia Gravis—A Rare Combination of Autoimmune Diseases in Taiwan

  • Chang, Kuo-Hsuan
  • Lyu, Rong-Kuo
  • Ro, Long-Sun
  • Wu, Yih-Ru
  • Chen, Chiung-Mei
Publication date
December 2006
Publisher
Formosan Medical Association & Elsevier. Published by Elsevier (Singapore) Pte Ltd

Abstract

About 5-10% of patients with myasthenia gravis concomitantly have other autoimmune diseases. However, the coexistence of myasthenia gravis and pernicious anemia is rare. Here, we report a 73-year-old Taiwanese woman who developed myasthenia gravis 5 months after the onset of pernicious anemia. Her myasthenic and pernicious anemia symptoms markedly improved after pyridostigmine, prednisolone and hydroxo-cobalamine treatment. It is important to recognize concurrence of myasthenia gravis and pernicious anemia in the same patient because the therapeutic results for both diseases are rewarding

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