Programmed necrosis has long been recognized as a crucial component of animal development; however, the signaling pathway beyond the protein kinases RIP1 and RIP3 remains largely unknown. Sun et al. and Wang et al. now identify critical factors downstream of RIP1 and RIP3 in programmed necrosis, extending our understanding of this form of cell death
The molecular mechanisms involved in induced pluripotent stem cells (iPSCs) generation are poorly un...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
Some lethal stimuli can induce either apoptosis or necrosis, depending on the cell type and/or exper...
Some lethal stimuli can induce either apoptosis or necrosis, depending on the cell type and/or exper...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
SummarySmac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a ca...
Cell proliferation and cell death are integral elements in maintaining homeostatic balance in metazo...
The lab of Jurg Tschopp was the first to report on the crucial role of receptor-interacting protein ...
Programmed cell death is the process by which an individual cell in a multicellular organism commits...
SummaryProgrammed necrosis is a form of caspase-independent cell death whose molecular regulation is...
SummarySmac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a ca...
The receptor-interacting protein kinase 3 (RIP3/RIPK3) has emerged as a critical regulator of progra...
The molecular mechanisms involved in induced pluripotent stem cells (iPSCs) generation are poorly un...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
Some lethal stimuli can induce either apoptosis or necrosis, depending on the cell type and/or exper...
Some lethal stimuli can induce either apoptosis or necrosis, depending on the cell type and/or exper...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor pro...
SummarySmac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a ca...
Cell proliferation and cell death are integral elements in maintaining homeostatic balance in metazo...
The lab of Jurg Tschopp was the first to report on the crucial role of receptor-interacting protein ...
Programmed cell death is the process by which an individual cell in a multicellular organism commits...
SummaryProgrammed necrosis is a form of caspase-independent cell death whose molecular regulation is...
SummarySmac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a ca...
The receptor-interacting protein kinase 3 (RIP3/RIPK3) has emerged as a critical regulator of progra...
The molecular mechanisms involved in induced pluripotent stem cells (iPSCs) generation are poorly un...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
During the past decade, cell death researchers have witnessed a gradual but deep conceptual revoluti...
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