Although cells dying by apoptosis expose the classical “eat me” signal phosphatidylserine (PS), a phagocytic transmembrane receptor for PS has proved elusive. Now cell and structural studies (Kobayashi et al. [2007] and Santiago et al. [2007] in this issue of Immunity) implicate the type I molecule TIM-4
Dying cells actively attract professional phagocytes by sending out soluble ‘find-me ’ signals. The ...
Apoptotic cells are usually cleared by phagocytosis in vivo with a rapid and efficient process aimed...
Phosphatidylserine (PS) is a major component of membrane bilayers whose change in distribution betwe...
SummaryEngulfment of apoptotic cells is an active process coordinated by receptors on phagocytes and...
SummaryThe T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance. Here...
Phagocytes recognize apoptotic cells using cell surface receptors, and subsequently engulf these cel...
SummaryThe recognition of phosphatidylserine (PS) on apoptotic cells within tissues drives both thei...
The original article is available via the journal's website http://www.molbiolcell.org/content/25/9/...
[[sponsorship]]生物醫學科學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/...
Phosphatidylserine (PS), a phospholipid predominantly found in the inner leaflet of eukaryotic cellu...
Prompt and efficient clearance of apoptotic cells is necessary to prevent secondary necrosis of dyin...
ABSTRACT T-cell immunoglobulin mucin protein 4 (TIM4), a phosphatidylserine (PtdSer)-bind-ing recept...
Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protei...
Apoptosis has been clearly characterised by the ability to limit the activation of inflammatory resp...
Clearance of apoptotic cells by phagocytic neighbors is crucial for normal development of multicellu...
Dying cells actively attract professional phagocytes by sending out soluble ‘find-me ’ signals. The ...
Apoptotic cells are usually cleared by phagocytosis in vivo with a rapid and efficient process aimed...
Phosphatidylserine (PS) is a major component of membrane bilayers whose change in distribution betwe...
SummaryEngulfment of apoptotic cells is an active process coordinated by receptors on phagocytes and...
SummaryThe T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance. Here...
Phagocytes recognize apoptotic cells using cell surface receptors, and subsequently engulf these cel...
SummaryThe recognition of phosphatidylserine (PS) on apoptotic cells within tissues drives both thei...
The original article is available via the journal's website http://www.molbiolcell.org/content/25/9/...
[[sponsorship]]生物醫學科學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/...
Phosphatidylserine (PS), a phospholipid predominantly found in the inner leaflet of eukaryotic cellu...
Prompt and efficient clearance of apoptotic cells is necessary to prevent secondary necrosis of dyin...
ABSTRACT T-cell immunoglobulin mucin protein 4 (TIM4), a phosphatidylserine (PtdSer)-bind-ing recept...
Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protei...
Apoptosis has been clearly characterised by the ability to limit the activation of inflammatory resp...
Clearance of apoptotic cells by phagocytic neighbors is crucial for normal development of multicellu...
Dying cells actively attract professional phagocytes by sending out soluble ‘find-me ’ signals. The ...
Apoptotic cells are usually cleared by phagocytosis in vivo with a rapid and efficient process aimed...
Phosphatidylserine (PS) is a major component of membrane bilayers whose change in distribution betwe...
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