Detection of foreign DNA in the cell cytosol triggers potent antiviral responses. In this issue of Immunity, Li et al. (2013) provide new structural and biochemical data indicating that a cytosolic DNA sensor, cyclic GMP-AMP synthase (cGAS), is activated by DNA-induced dimerization
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...
The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) mediates innate immune responses against inv...
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...
Detection of foreign DNA in the cell cytosol triggers potent antiviral responses. In this issue of I...
Cytosolic DNA arising from intracellular bacterial or viral infections is a powerful pathogen-associ...
Cytosolic DNA arising from intracellular bacteria or viral infections is a powerful pathogen-associa...
SummaryThe presence of DNA in the cytoplasm is a danger signal that triggers immune and inflammatory...
Innate immune recognition of foreign nucleic acids induces protective interferon responses. Detectio...
SummaryCyclic GMP-AMP synthase (cGAS) is a cytosolic DNA sensor mediating innate antimicrobial immun...
The presence of DNA in the cytoplasm is a danger signal that triggers immune and inflammatory respon...
The presence of DNA in the cytoplasm of mammalian cells is perceived as a danger signal, alerting th...
SummaryInnate immune recognition of foreign nucleic acids induces protective interferon responses. D...
<div><p>The detection of cytosolic DNA, derived from pathogens or host cells, by cytosolic receptors...
The detection of cytosolic DNA, derived from pathogens or host cells, by cytosolic receptors is esse...
Cyclic GMP-AMP synthase (cGAS) is a predominant and ubiquitously expressed cytosolic onfirmedDNA sen...
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...
The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) mediates innate immune responses against inv...
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...
Detection of foreign DNA in the cell cytosol triggers potent antiviral responses. In this issue of I...
Cytosolic DNA arising from intracellular bacterial or viral infections is a powerful pathogen-associ...
Cytosolic DNA arising from intracellular bacteria or viral infections is a powerful pathogen-associa...
SummaryThe presence of DNA in the cytoplasm is a danger signal that triggers immune and inflammatory...
Innate immune recognition of foreign nucleic acids induces protective interferon responses. Detectio...
SummaryCyclic GMP-AMP synthase (cGAS) is a cytosolic DNA sensor mediating innate antimicrobial immun...
The presence of DNA in the cytoplasm is a danger signal that triggers immune and inflammatory respon...
The presence of DNA in the cytoplasm of mammalian cells is perceived as a danger signal, alerting th...
SummaryInnate immune recognition of foreign nucleic acids induces protective interferon responses. D...
<div><p>The detection of cytosolic DNA, derived from pathogens or host cells, by cytosolic receptors...
The detection of cytosolic DNA, derived from pathogens or host cells, by cytosolic receptors is esse...
Cyclic GMP-AMP synthase (cGAS) is a predominant and ubiquitously expressed cytosolic onfirmedDNA sen...
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...
The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) mediates innate immune responses against inv...
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. I...