AbstractThe Filamin family of actin binding proteins is required to maintain cell shape and promote cell locomotion. Using the Drosophila ovary, we provide a detailed description of Filamin-deficient cells during morphogenesis. Reduced expression of Filamin in follicle cells causes defects in the initial encapsulation of germline cysts and in the migration of border cells through the germline cyst. However, follicle cell morphogenesis is unaffected by point mutations that produce truncated Filamin proteins. In addition, mutant follicle cell movements can be partially rescued by a transgene encoding only the actin-binding domain and the first six filamin repeats. These data show that Filamin function in cell motility can be provided by a tru...
Planar cell polarity is an important characteristic of many epithelia. In the Drosophila wing, eye a...
All insect ovaries are composed of functional units called ovarioles, which contain sequentially dev...
The FERM domain protein Okapi (Oka) is important for normal Drosophila oogenesis. I found that Oka i...
AbstractThe Filamin family of actin binding proteins is required to maintain cell shape and promote ...
Cells integrate mechanical properties of their surroundings to form multicellular, three-dimensional...
AbstractBackground: The ring canals in the ovary of the fruit fly Drosophila provide a versatile sys...
AbstractTheovarian tumorgene is required during both early and late stages of oogenesis. Mutations p...
AbstractBackground: Regulation of actin structures is instrumental in maintaining proper cytoarchite...
Identifying genes involved in the control of adherens junction (AJ) remodeling is essential to under...
AbstractDuring development, cells craft an impressive array of actin-based structures, mediating eve...
AbstractThe adult ovary of Drosophila is composed of approximately 20 parallel repetitive structures...
F-actin networks are important structural determinants of cell shape and morphogenesis. They are reg...
AbstractBackground: Motor proteins of the minus end-directed cytoplasmic dynein and plus end-directe...
Okapi (Oka) is a Drosophila melanogaster FERM domain protein that is essential for oogenesis. oka (C...
AbstractBicaudal-D (Bic-D) is required for the transport of determinant mRNAs and proteins to the pr...
Planar cell polarity is an important characteristic of many epithelia. In the Drosophila wing, eye a...
All insect ovaries are composed of functional units called ovarioles, which contain sequentially dev...
The FERM domain protein Okapi (Oka) is important for normal Drosophila oogenesis. I found that Oka i...
AbstractThe Filamin family of actin binding proteins is required to maintain cell shape and promote ...
Cells integrate mechanical properties of their surroundings to form multicellular, three-dimensional...
AbstractBackground: The ring canals in the ovary of the fruit fly Drosophila provide a versatile sys...
AbstractTheovarian tumorgene is required during both early and late stages of oogenesis. Mutations p...
AbstractBackground: Regulation of actin structures is instrumental in maintaining proper cytoarchite...
Identifying genes involved in the control of adherens junction (AJ) remodeling is essential to under...
AbstractDuring development, cells craft an impressive array of actin-based structures, mediating eve...
AbstractThe adult ovary of Drosophila is composed of approximately 20 parallel repetitive structures...
F-actin networks are important structural determinants of cell shape and morphogenesis. They are reg...
AbstractBackground: Motor proteins of the minus end-directed cytoplasmic dynein and plus end-directe...
Okapi (Oka) is a Drosophila melanogaster FERM domain protein that is essential for oogenesis. oka (C...
AbstractBicaudal-D (Bic-D) is required for the transport of determinant mRNAs and proteins to the pr...
Planar cell polarity is an important characteristic of many epithelia. In the Drosophila wing, eye a...
All insect ovaries are composed of functional units called ovarioles, which contain sequentially dev...
The FERM domain protein Okapi (Oka) is important for normal Drosophila oogenesis. I found that Oka i...