A paper by Martinvalet et al. (2005) in this issue of Immunity examines the mechanisms used by granzyme A to kill target cells after its cytoplasmic injection by cytotoxic lymphocytes. They show that this protease induces mitochondrial damage and generation of reactive oxygen species that are necessary for cell death
The caspase family of cysteine proteases becomes activated in response to diverse cellular insults a...
The granule-exocytosis pathway is the main mechanism via which cytotoxic lymphocytes exert their ant...
Granzymes are cell death-inducing serine proteases released from cytotoxic granules of cytotoxic T l...
Granule-mediated cytotoxicity is the major mechanism for lymphocytes to kill viruses, intracellular ...
The induction of caspase-independent cell death by killer lymphocytes involves the serine protease g...
The induction of caspase-independent cell death by killer lymphocytes involves the serine protease g...
Cell-mediated cytotoxicity is an essential immune defense mechanism to fight against viral, bacteria...
The mitochondria represent an integration and amplification hub for various death pathways including...
Granzymes (gzm) are major components of the granules of cytolytic lymphocytes, natural killer and cy...
Granzyme A: cell death–inducing protease, proinflammatory agent, or both? We recently showed that gr...
Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pi...
THESIS 8738Cytotoxic Lymphocytes (CTL) and Natural Killer (NK) cells provide the body with a powerfu...
Granzyme B (gzmB) of cytotoxic T lymphocytes (CTL) is essential for recovery from intracellular path...
© 2011 Dr. Olivia SusantoCytotoxic lymphocytes (CL) are an essential component of the immune system ...
Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell...
The caspase family of cysteine proteases becomes activated in response to diverse cellular insults a...
The granule-exocytosis pathway is the main mechanism via which cytotoxic lymphocytes exert their ant...
Granzymes are cell death-inducing serine proteases released from cytotoxic granules of cytotoxic T l...
Granule-mediated cytotoxicity is the major mechanism for lymphocytes to kill viruses, intracellular ...
The induction of caspase-independent cell death by killer lymphocytes involves the serine protease g...
The induction of caspase-independent cell death by killer lymphocytes involves the serine protease g...
Cell-mediated cytotoxicity is an essential immune defense mechanism to fight against viral, bacteria...
The mitochondria represent an integration and amplification hub for various death pathways including...
Granzymes (gzm) are major components of the granules of cytolytic lymphocytes, natural killer and cy...
Granzyme A: cell death–inducing protease, proinflammatory agent, or both? We recently showed that gr...
Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pi...
THESIS 8738Cytotoxic Lymphocytes (CTL) and Natural Killer (NK) cells provide the body with a powerfu...
Granzyme B (gzmB) of cytotoxic T lymphocytes (CTL) is essential for recovery from intracellular path...
© 2011 Dr. Olivia SusantoCytotoxic lymphocytes (CL) are an essential component of the immune system ...
Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell...
The caspase family of cysteine proteases becomes activated in response to diverse cellular insults a...
The granule-exocytosis pathway is the main mechanism via which cytotoxic lymphocytes exert their ant...
Granzymes are cell death-inducing serine proteases released from cytotoxic granules of cytotoxic T l...
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