A Randomized Comparison of Selective Broadband UVB and Narrowband UVB in the Treatment of Psoriasis
- Kirke, Sandra M.
- Lowder, Sharon
- Lloyd, James J.
- Diffey, Brian L.
- Matthews, John N.S.
- Farr, Peter M.
DOIAbstract
UVB is widely used to treat psoriasis. Conventional broadband UVB lamps are less effective than narrowband UVB lamps, which have an emission peak at 311nm. The long-term safety of narrowband UVB phototherapy is uncertain. “Selective” broadband UVB lamps, which have little emission <290nm, are also available, but have not been adequately compared to narrowband UVB lamps. We performed a randomized comparison of narrowband UVB (TL-01 lamps) and selective broadband UVB (UV6 lamps) in 100 patients with psoriasis. The median number of exposures for clearance was 28.4 for TL-01 and 30.4 for UV6 (ratio of the medians 0.93; 95% confidence interval (CI) 0.80, 1.09; P=0.39). No significant difference was found in the proportion of patients achieving c...
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