Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4

Handa, Hiroshi
Watanabe, Hajime
Suzuki, Yoshiaki
Hirose, Susumu

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Publication date

May 1989

DOI

10.1016/0014-5793(89)80006-7

Publisher

Published by Elsevier B.V.

Abstract

AbstractThe effect of DNA supercoiling on in vitro transcription from the early region 4 (E4) promoter of adenovirus type 5 (Ad5) has been investigated by using a cell-free transcription system that maintains supercoiled DNA templates. The supercoiled DNAs yield several-fold higher levels of E4 transcripts and more faithfully reflect the regulation of in vivo transcription than the linear DNAs

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Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4

Abstract

Extracted data

Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4

Abstract

Extracted data

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