The mechanisms that direct cell-type-specific peroxisome proliferator-activated receptor (PPAR) gene programs are poorly understood. In this issue of Immunity, Szanto et al. (2010) identify signal transducer and activator of transcription 6 as a transcriptional switch that licenses PPARγ-dependent gene expression in macrophages and dendritic cells
International audiencePeroxisome proliferator-activated receptors (PPARs) are ligand-activated trans...
One of the key cell types behind both the acute and resolution phase of inflammation is the macropha...
Infection with different pathogens can result in activation of PPARγ and LXR. Pathways regulated by ...
The mechanisms that direct cell-type-specific peroxisome proliferator-activated receptor (PPAR) gene...
SummaryPeroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription facto...
SummaryPeroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription facto...
Includes bibliographical references (leaves 70-81)Peroxisome proliferators activated receptors (PPAR...
We used a combination of expression microarray and Northern blot analyses to identify target genes f...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
NRs have a highly conserved structure with an N-terminal transactivation domain and a DNA-binding do...
Macrophages represent the most diverse cell type in biology. They adapt selectively to many stimuli ...
International audienceAlthough peroxisome proliferator-activated receptor γ (PPARγ) has anti-inflamm...
International audiencePeroxisome proliferator-activated receptors (PPARs) are ligand-activated trans...
International audiencePeroxisome proliferator-activated receptors (PPARs) are ligand-activated trans...
One of the key cell types behind both the acute and resolution phase of inflammation is the macropha...
Infection with different pathogens can result in activation of PPARγ and LXR. Pathways regulated by ...
The mechanisms that direct cell-type-specific peroxisome proliferator-activated receptor (PPAR) gene...
SummaryPeroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription facto...
SummaryPeroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription facto...
Includes bibliographical references (leaves 70-81)Peroxisome proliferators activated receptors (PPAR...
We used a combination of expression microarray and Northern blot analyses to identify target genes f...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found th...
NRs have a highly conserved structure with an N-terminal transactivation domain and a DNA-binding do...
Macrophages represent the most diverse cell type in biology. They adapt selectively to many stimuli ...
International audienceAlthough peroxisome proliferator-activated receptor γ (PPARγ) has anti-inflamm...
International audiencePeroxisome proliferator-activated receptors (PPARs) are ligand-activated trans...
International audiencePeroxisome proliferator-activated receptors (PPARs) are ligand-activated trans...
One of the key cell types behind both the acute and resolution phase of inflammation is the macropha...
Infection with different pathogens can result in activation of PPARγ and LXR. Pathways regulated by ...
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