AbstractA recombinant rat thyroid hormone receptor α (TRα or c-ErbAα1) was produced in E. coli as a non-mutated,non-fusioned protein and obtained as an efficient DNA and T3 binding protein that could be easily handled in a buffer-soluble state (rec-TRα). It was found that nuclear extracts (NE) added to rec-TRα markedly amplified not only DNA binding, which has been well documented, but also T3 binding (increased binding site concentration), which has not yet been reported. This T3 binding amplifying effect on rec-TRα occurs at low NE protein concentrations that produce no or minimal endogenous TR with respect to rec-TR, while similar concentrations of other proteins (e.g. ovalbumin or cytosol) only moderately enhanced T3 binding. The T3 bin...
The thyroid hormone receptor a1 (TRa1) is a nuclear receptor for thyroid hormone that shuttles rapid...
In Xenopus oocytes, the rat thyroid hormone receptor α (rTR α), but not its oncogenic homolog v-ErbA...
Thyroid hormone receptor (TR) is a member of the nuclear receptor superfamily that shuttles between ...
AbstractA recombinant rat thyroid hormone receptor α (TRα or c-ErbAα1) was produced in E. coli as a ...
Thyroid hormone (T3) is critical for proper growth, development and, maintenance of metabolism in ad...
The thyroid hormone receptor (TR) is a member of the nuclear hormone receptor (NHR) superfamily. Mem...
Thyroid hormones (THs) control a wide range of physiological functions essential for metabolism, gro...
Thyroid Hormone Receptor ?1 (TR?) is a nuclear hormone receptor that plays a vital role in different...
The erbA superfamily constitutes a group of ligand-inducible transcriptional activators that include...
Thyroid hormone receptors (TRs), such as TRα1, TRβ1, and TRβ2, are members of the nuclear receptor s...
ErbA/thyroid hormone receptor is a nuclear receptor that can affect transcription from promoters con...
The thyroid hormone receptor (TR) is a nuclear receptor that plays a critical role in human developm...
Thyroid hormone (T3) receptor (TR) is a ligand-dependent transcription factor that acts through spec...
Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that regulate target gene...
The present review traces the road leading to discovery of L-thyroxine, thyroid hormone (3,5,3´-trii...
The thyroid hormone receptor a1 (TRa1) is a nuclear receptor for thyroid hormone that shuttles rapid...
In Xenopus oocytes, the rat thyroid hormone receptor α (rTR α), but not its oncogenic homolog v-ErbA...
Thyroid hormone receptor (TR) is a member of the nuclear receptor superfamily that shuttles between ...
AbstractA recombinant rat thyroid hormone receptor α (TRα or c-ErbAα1) was produced in E. coli as a ...
Thyroid hormone (T3) is critical for proper growth, development and, maintenance of metabolism in ad...
The thyroid hormone receptor (TR) is a member of the nuclear hormone receptor (NHR) superfamily. Mem...
Thyroid hormones (THs) control a wide range of physiological functions essential for metabolism, gro...
Thyroid Hormone Receptor ?1 (TR?) is a nuclear hormone receptor that plays a vital role in different...
The erbA superfamily constitutes a group of ligand-inducible transcriptional activators that include...
Thyroid hormone receptors (TRs), such as TRα1, TRβ1, and TRβ2, are members of the nuclear receptor s...
ErbA/thyroid hormone receptor is a nuclear receptor that can affect transcription from promoters con...
The thyroid hormone receptor (TR) is a nuclear receptor that plays a critical role in human developm...
Thyroid hormone (T3) receptor (TR) is a ligand-dependent transcription factor that acts through spec...
Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that regulate target gene...
The present review traces the road leading to discovery of L-thyroxine, thyroid hormone (3,5,3´-trii...
The thyroid hormone receptor a1 (TRa1) is a nuclear receptor for thyroid hormone that shuttles rapid...
In Xenopus oocytes, the rat thyroid hormone receptor α (rTR α), but not its oncogenic homolog v-ErbA...
Thyroid hormone receptor (TR) is a member of the nuclear receptor superfamily that shuttles between ...