AbstractNeuropeptide Y (NPY) is one of the most abundant peptides in the central nervous system of mammals. It belongs to the best-conserved peptides in nature, i.e., the amino acid sequences of even evolutionary widely separated species are very similar to each other. Using porcine NPY, which differs from human NPY only at position 17 (a leucine residue exchanged for a methionine), labeled with a TOAC spin probe at the 2nd, 32nd, or 34th positions of the peptide backbone, the membrane binding and penetration of NPY was determined using EPR and NMR spectroscopy. The vesicular membranes were composed of phosphatidylcholine and phosphatidylserine at varying mixing ratios. From the analysis of the EPR line shapes, the spectral contributions of...
AbstractMolecular mechanism of the binding of neuropeptide achatin-I (Gly-D-Phe-Ala-Asp) to large un...
AbstractThe interaction of a 19 amino acid vesicular stomatitis virus G protein fragment (GTWLNPGFPP...
High-resolution31P magic angle spinning (MAS) NMR spectroscopy is presented as a direct and non-pert...
AbstractNeuropeptide Y (NPY) is one of the most abundant peptides in the central nervous system of m...
The association of neuropeptide Y (NPY) at the air/water interface and with phospholipid monolayers ...
The association of neuropeptide Y (NPY) with air/water interfaces and with phospholipid monolayers o...
Detailed molecular knowledge of the complex dynamics of biological processes such as folding and the...
The significance of information gained from the solution structure of peptides for pharmaceutical re...
Binding of neurohormones from the NPY family to their receptors, the so-called Y receptors, that bel...
AbstractBy using monoiodinated radioligands of both intact neuropeptide Y (NPY) and of a long C-term...
Interactions between peptides and biological lipid membranes play a crucial role in many cellular pr...
AbstractThe attractive interaction between basic protein domains and membranes containing acidic lip...
In contrast to the static snapshots provided by protein crystallography, G protein-coupled receptors...
AbstractThe attractive interaction between basic protein domains and membranes containing acidic lip...
AbstractThe membrane interactions and position of a positively charged and highly aromatic peptide d...
AbstractMolecular mechanism of the binding of neuropeptide achatin-I (Gly-D-Phe-Ala-Asp) to large un...
AbstractThe interaction of a 19 amino acid vesicular stomatitis virus G protein fragment (GTWLNPGFPP...
High-resolution31P magic angle spinning (MAS) NMR spectroscopy is presented as a direct and non-pert...
AbstractNeuropeptide Y (NPY) is one of the most abundant peptides in the central nervous system of m...
The association of neuropeptide Y (NPY) at the air/water interface and with phospholipid monolayers ...
The association of neuropeptide Y (NPY) with air/water interfaces and with phospholipid monolayers o...
Detailed molecular knowledge of the complex dynamics of biological processes such as folding and the...
The significance of information gained from the solution structure of peptides for pharmaceutical re...
Binding of neurohormones from the NPY family to their receptors, the so-called Y receptors, that bel...
AbstractBy using monoiodinated radioligands of both intact neuropeptide Y (NPY) and of a long C-term...
Interactions between peptides and biological lipid membranes play a crucial role in many cellular pr...
AbstractThe attractive interaction between basic protein domains and membranes containing acidic lip...
In contrast to the static snapshots provided by protein crystallography, G protein-coupled receptors...
AbstractThe attractive interaction between basic protein domains and membranes containing acidic lip...
AbstractThe membrane interactions and position of a positively charged and highly aromatic peptide d...
AbstractMolecular mechanism of the binding of neuropeptide achatin-I (Gly-D-Phe-Ala-Asp) to large un...
AbstractThe interaction of a 19 amino acid vesicular stomatitis virus G protein fragment (GTWLNPGFPP...
High-resolution31P magic angle spinning (MAS) NMR spectroscopy is presented as a direct and non-pert...