SummaryDirected reprogramming of differentiated cells allows the generation of specific cell types for therapeutics and can provide unexpected insights into development. A recent study demonstrates that efficient reprogramming of Caenorhabditis elegans germ cells into neurons can be achieved by knocking down a histone chaperone gene and ectopic expression of a terminal selector transcription factor
International audienceCells can change identity during normal development, in response to tissue dam...
Recent researches have identified multiple transcription factors as permissible reprogramming factor...
These data relate to the findings published in "Transient and permanent reconfiguration of chromatin...
The ability of transcription factors to directly reprogram the identity of cell types is usually res...
SummaryDirected reprogramming of differentiated cells allows the generation of specific cell types f...
Chromatin regulators play important roles in the safeguarding of cell identities by opposing the ind...
Chromatin regulators play important roles in the safeguarding of cell identities by opposing the ind...
Cellular reprogramming has the potential to treat numerous degenerative diseases and repair injured ...
How specific cell types can be directly converted into other distinct cell types is a matter of inte...
Small-molecules can control cell fate in vivo and may allow directed induction of desired cell types...
Generating needed cell types using cellular reprogramming is a promising strategy for restoring tiss...
The identity of individual cell types in a multicellular organism appears to be continuously maintai...
Cellular reprogramming drives cells from one stable identity to a new cell fate. By generating a div...
Cellular reprogramming drives cells from one stable identity to a new cell fate. By generating a div...
Cell fate conversion by the forced overexpression of transcription factors (TFs) is a process known ...
International audienceCells can change identity during normal development, in response to tissue dam...
Recent researches have identified multiple transcription factors as permissible reprogramming factor...
These data relate to the findings published in "Transient and permanent reconfiguration of chromatin...
The ability of transcription factors to directly reprogram the identity of cell types is usually res...
SummaryDirected reprogramming of differentiated cells allows the generation of specific cell types f...
Chromatin regulators play important roles in the safeguarding of cell identities by opposing the ind...
Chromatin regulators play important roles in the safeguarding of cell identities by opposing the ind...
Cellular reprogramming has the potential to treat numerous degenerative diseases and repair injured ...
How specific cell types can be directly converted into other distinct cell types is a matter of inte...
Small-molecules can control cell fate in vivo and may allow directed induction of desired cell types...
Generating needed cell types using cellular reprogramming is a promising strategy for restoring tiss...
The identity of individual cell types in a multicellular organism appears to be continuously maintai...
Cellular reprogramming drives cells from one stable identity to a new cell fate. By generating a div...
Cellular reprogramming drives cells from one stable identity to a new cell fate. By generating a div...
Cell fate conversion by the forced overexpression of transcription factors (TFs) is a process known ...
International audienceCells can change identity during normal development, in response to tissue dam...
Recent researches have identified multiple transcription factors as permissible reprogramming factor...
These data relate to the findings published in "Transient and permanent reconfiguration of chromatin...
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