An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues—whether used alone or in combination with currently approved drugs—would change the way we treat cancer. In this issue, Fischer et al. (2007) offer compelling evidence that a monoclonal antibody against placental growth factor (PlGF), a member of the VEGF family, has such potential in mice
Angiogenesis, the formation of new capillaries from preexisting blood vessels, plays an important ro...
peer reviewedOur findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatm...
An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues—whe...
Novel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy and mi...
SummaryIt has been recently reported that treatment with an anti-placenta growth factor (PlGF) antib...
Novel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy and mi...
SummaryNovel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy...
Novel antiangiogenic strategies with comple-mentary mechanisms are needed to maximize efficacy and m...
Placental growth factor (PLGF) belongs to the VEGF family, which among the three VEGF receptors bind...
Background: Inhibition of angiogenesis is currently hot topic in the search for an effective treatm...
Many proliferative diseases, most typically cancer, are driven by uncontrolled blood vessel growth. ...
Aims: The vascular endothelial growth factor homologue placental growth factor (PlGF) is a pleiotrop...
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family t...
Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been...
Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been...
Angiogenesis, the formation of new capillaries from preexisting blood vessels, plays an important ro...
peer reviewedOur findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatm...
An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues—whe...
Novel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy and mi...
SummaryIt has been recently reported that treatment with an anti-placenta growth factor (PlGF) antib...
Novel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy and mi...
SummaryNovel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy...
Novel antiangiogenic strategies with comple-mentary mechanisms are needed to maximize efficacy and m...
Placental growth factor (PLGF) belongs to the VEGF family, which among the three VEGF receptors bind...
Background: Inhibition of angiogenesis is currently hot topic in the search for an effective treatm...
Many proliferative diseases, most typically cancer, are driven by uncontrolled blood vessel growth. ...
Aims: The vascular endothelial growth factor homologue placental growth factor (PlGF) is a pleiotrop...
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family t...
Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been...
Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been...
Angiogenesis, the formation of new capillaries from preexisting blood vessels, plays an important ro...
peer reviewedOur findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatm...
An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues—whe...