Chewing the fat: A case report on intravenous lipid emulsion to reverse cardiotoxicity from intentional amitriptyline overdose.

AbstractIntroductionTricyclic antidepressant overdoses are a common presenting problem to emergency centres in South Africa.Case historyA 20-year-old female was brought to the emergency centre in status epilepticus due to tricyclic antidepressant toxicity.DiscussionToxicity was manifested as severe haemodynamic instability that did not respond to standard therapy, and was subsequently treated with intravenous fat emulsion (ILE) therapy. The patient recovered with a survival to hospital discharge, neurologically intact