Exquisite control of intestinal iron absorption prevents iron deficiency and toxic iron overload. Absorption is modulated by a circulating hormone, hepcidin, which inactivates the iron transporter ferroportin. In this issue of Cell Metabolism, Vanoaica and colleagues show that absorption is also regulated within the intestinal epithelium, through production of the iron-sequestering protein H-ferritin
SummaryMammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by...
Two studies (Shah et al., 2009; Mastrogiannaki et al., 2009) show that the hypoxia inducible factor ...
Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis re...
Exquisite control of intestinal iron absorption prevents iron deficiency and toxic iron overload. Ab...
SummaryTo maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought...
SummaryTo maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought...
To maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought to be ...
Iron homeostasis in mammals is principally maintained by the regulation of intestinal iron absorptio...
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed ...
Purpose of review Intestinal iron absorption is an essential physiological process that is regulated...
SummaryMammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by...
Mammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by iron r...
Despite its abundance in the environment, iron is poorly bioavailable and subject to strict conserva...
The intestinal absorption of the essential trace element iron and its mobilization from storage site...
In recent years, a number of components of the iron absorption pathway have been identified, greatly...
SummaryMammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by...
Two studies (Shah et al., 2009; Mastrogiannaki et al., 2009) show that the hypoxia inducible factor ...
Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis re...
Exquisite control of intestinal iron absorption prevents iron deficiency and toxic iron overload. Ab...
SummaryTo maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought...
SummaryTo maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought...
To maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought to be ...
Iron homeostasis in mammals is principally maintained by the regulation of intestinal iron absorptio...
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed ...
Purpose of review Intestinal iron absorption is an essential physiological process that is regulated...
SummaryMammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by...
Mammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by iron r...
Despite its abundance in the environment, iron is poorly bioavailable and subject to strict conserva...
The intestinal absorption of the essential trace element iron and its mobilization from storage site...
In recent years, a number of components of the iron absorption pathway have been identified, greatly...
SummaryMammalian iron metabolism is regulated systemically by the hormone hepcidin and cellularly by...
Two studies (Shah et al., 2009; Mastrogiannaki et al., 2009) show that the hypoxia inducible factor ...
Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis re...
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