Modifications of mRNAs can have a profound effect on cellular function and differentiation. In this issue of Cell Stem Cell, Batista et al. (2014) describe fundamental parameters of N6-methyl-adenosine modification of mRNAs in embryonic stem cells and provide strong evidence that modification plays a role in exit from pluripotency toward differentiation
Background: The therapeutic use of multipotent stem cells depends on their differentiation potential...
SummaryN6-methyl-adenosine (m6A) is the most abundant modification on messenger RNAs and is linked t...
Epigenetic modifications of DNA and chromatin are long known to control stem cell differentiation an...
Modifications of mRNAs can have a profound effect on cellular function and differentiation. In this ...
Vast emerging evidences are linking the base modifications and determination of stem cell fate such ...
Sequence databases and transcriptome-wide mapping have revealed different reversible and dynamic che...
Sequence databases and transcriptome-wide mapping have revealed different reversible and dynamic che...
SummaryN6-methyl-adenosine (m6A) is the most abundant modification on messenger RNAs and is linked t...
RNA N6-methyladenosine (m6A) modification has important regulatory roles in determining cell fate. T...
stem cells are defined by two fundamental properties: self-renewal and pluripotency or multipotency....
N6-methyl-adenosine (m[superscript 6]A) is the most abundant modification on messenger RNAs and is l...
Epigenetic modifications play a significant role in determining the fate of stem cells and in direct...
BACKGROUND: The therapeutic use of multipotent stem cells depends on their differentiation potential...
Abstract Deficiency of the N6‐methyladenosine (m6A) methyltransferase complex results in global redu...
BACKGROUND: The therapeutic use of multipotent stem cells depends on their differentiation potential...
Background: The therapeutic use of multipotent stem cells depends on their differentiation potential...
SummaryN6-methyl-adenosine (m6A) is the most abundant modification on messenger RNAs and is linked t...
Epigenetic modifications of DNA and chromatin are long known to control stem cell differentiation an...
Modifications of mRNAs can have a profound effect on cellular function and differentiation. In this ...
Vast emerging evidences are linking the base modifications and determination of stem cell fate such ...
Sequence databases and transcriptome-wide mapping have revealed different reversible and dynamic che...
Sequence databases and transcriptome-wide mapping have revealed different reversible and dynamic che...
SummaryN6-methyl-adenosine (m6A) is the most abundant modification on messenger RNAs and is linked t...
RNA N6-methyladenosine (m6A) modification has important regulatory roles in determining cell fate. T...
stem cells are defined by two fundamental properties: self-renewal and pluripotency or multipotency....
N6-methyl-adenosine (m[superscript 6]A) is the most abundant modification on messenger RNAs and is l...
Epigenetic modifications play a significant role in determining the fate of stem cells and in direct...
BACKGROUND: The therapeutic use of multipotent stem cells depends on their differentiation potential...
Abstract Deficiency of the N6‐methyladenosine (m6A) methyltransferase complex results in global redu...
BACKGROUND: The therapeutic use of multipotent stem cells depends on their differentiation potential...
Background: The therapeutic use of multipotent stem cells depends on their differentiation potential...
SummaryN6-methyl-adenosine (m6A) is the most abundant modification on messenger RNAs and is linked t...
Epigenetic modifications of DNA and chromatin are long known to control stem cell differentiation an...
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