SummaryLeßmann et al. present a chiral natural-product-derived library of α,β-unsaturated δ-lactones obtained through stereoselective synthesis on a solid support [1]. Phenotypic screening of this compound collection provided new modulators of cell cycle progression and of viral cell entry with high hit rates
107 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1980.A general synthetic approach ...
Over the years, it has been shown that natural products which are capable of acting as modulators (i...
In order to mimic the complexity of natural products, we designed and obtained with simple synthetic...
SummaryLeßmann et al. present a chiral natural-product-derived library of α,β-unsaturated δ-lactones...
The underlying frameworks of natural product classes with multiple biological activities can be rega...
SummaryThe underlying frameworks of natural product classes with multiple biological activities can ...
In this genomics and proteomics age, highly functionalized natural products or natural-product-like ...
The total synthesis of the bioactive natural product (+)-Sch 642305 has been achieved from a readily...
The sesquiterpene lactones cover a diverse and pharmacologically important diversity space. In parti...
Natural products that act as highly specific, small-molecule protein-binding agents and as modulator...
New, regio- and diastereoselective processes are described in which readily accessible starting mate...
Contains fulltext : mmubn000001_179715879.pdf (publisher's version ) (Open Access)...
Stereochemistry and enantiopurity are important aspects of biologically active molecules. Our resear...
We are involved in the synthesis of new compounds potentially able to inhibit different biological t...
Chirality is an inherent aspect of biology, and interactions between biomolecules are often influenc...
107 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1980.A general synthetic approach ...
Over the years, it has been shown that natural products which are capable of acting as modulators (i...
In order to mimic the complexity of natural products, we designed and obtained with simple synthetic...
SummaryLeßmann et al. present a chiral natural-product-derived library of α,β-unsaturated δ-lactones...
The underlying frameworks of natural product classes with multiple biological activities can be rega...
SummaryThe underlying frameworks of natural product classes with multiple biological activities can ...
In this genomics and proteomics age, highly functionalized natural products or natural-product-like ...
The total synthesis of the bioactive natural product (+)-Sch 642305 has been achieved from a readily...
The sesquiterpene lactones cover a diverse and pharmacologically important diversity space. In parti...
Natural products that act as highly specific, small-molecule protein-binding agents and as modulator...
New, regio- and diastereoselective processes are described in which readily accessible starting mate...
Contains fulltext : mmubn000001_179715879.pdf (publisher's version ) (Open Access)...
Stereochemistry and enantiopurity are important aspects of biologically active molecules. Our resear...
We are involved in the synthesis of new compounds potentially able to inhibit different biological t...
Chirality is an inherent aspect of biology, and interactions between biomolecules are often influenc...
107 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1980.A general synthetic approach ...
Over the years, it has been shown that natural products which are capable of acting as modulators (i...
In order to mimic the complexity of natural products, we designed and obtained with simple synthetic...
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