Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Nature, Victor and colleagues describe that anti-PD-L1 combats adaptive immune resistance upon localized radiation plus anti-CTLA-4 therapy. The superior activity of radiation and dual immune checkpoint blockade is mediated by non-redundant immune mechanisms in cancer
Radiation oncology has recently seen tremendous technical advances, resulting in increasing cancer c...
Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagno...
UnlabelledAdaptive immune resistance is a process in which the cancer changes its phenotype in respo...
Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Natur...
Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Natur...
Literature experiences in cancer treatment usually deal with either targeting the tumour cell or the...
Immune checkpoint blockade results in T cell antitumor responses but most patients fail to respond. ...
Since the approval of anti-CTLA4 therapy (ipilimumab) for late-stage melanoma in 2011, the developme...
Immune checkpoint inhibitors have been associated with long-term complete responses leading to impro...
Radiation therapy is an established and effective anti-cancer treatment modality. Extensive pre-clin...
Immune checkpoint blockade has recently emerged as an important therapeutic approach to the manageme...
Purpose of reviewThe immunomodulatory effects of ionizing radiation have long been recognized; howev...
There is growing evidence that tumor-specific immune responses play an important role in anti-cancer...
There is a very strong biological and pre-clinical rationale for combining radiotherapy with immune ...
There is a very strong biological and pre-clinical rationale for combining radiotherapy with immune ...
Radiation oncology has recently seen tremendous technical advances, resulting in increasing cancer c...
Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagno...
UnlabelledAdaptive immune resistance is a process in which the cancer changes its phenotype in respo...
Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Natur...
Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Natur...
Literature experiences in cancer treatment usually deal with either targeting the tumour cell or the...
Immune checkpoint blockade results in T cell antitumor responses but most patients fail to respond. ...
Since the approval of anti-CTLA4 therapy (ipilimumab) for late-stage melanoma in 2011, the developme...
Immune checkpoint inhibitors have been associated with long-term complete responses leading to impro...
Radiation therapy is an established and effective anti-cancer treatment modality. Extensive pre-clin...
Immune checkpoint blockade has recently emerged as an important therapeutic approach to the manageme...
Purpose of reviewThe immunomodulatory effects of ionizing radiation have long been recognized; howev...
There is growing evidence that tumor-specific immune responses play an important role in anti-cancer...
There is a very strong biological and pre-clinical rationale for combining radiotherapy with immune ...
There is a very strong biological and pre-clinical rationale for combining radiotherapy with immune ...
Radiation oncology has recently seen tremendous technical advances, resulting in increasing cancer c...
Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagno...
UnlabelledAdaptive immune resistance is a process in which the cancer changes its phenotype in respo...