Although histone acetylation is critical for maintaining embryonic stem cell pluripotency, the molecular machinery involved remains poorly understood. Li et al. (2012) now show that Mof, a MYST family histone acetyltransferase, functions as a coactivator of Nanog-mediated transcription, maintains the expression of pluripotency-associated genes, and primes developmental genes for differentiation
MOZ (also known as KAT6A and MYST3) is a histone acetyltransferase that is implicated in the develop...
© 2012 Dr. Bilal SheikhChromatin plays an integral role in regulating stem cells and embryonic devel...
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently...
Although histone acetylation is critical for maintaining embryonic stem cell pluripotency, the molec...
SummaryPluripotent embryonic stem cells (ESCs) maintain self-renewal and the potential for rapid res...
The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripoten...
MOF was first identified in <i>Drosophila melanogaster</i> as an important component of the dosage c...
The mammalian ortholog of the Drosophila MOF (males absent on the first) gene product is a histone H...
AbstractThe histone acetyltransferase Myst2 plays an important role in embryogenesis, but its functi...
Males absent on the first (MOF), also known as hMOF, MYST1, or KAT8, is a lysine acetyltransferase r...
Changes in chromatin structure and heritably regulating the gene expression by epigenetic mechanisms...
MOF (MYST1) is the major enzyme to catalyze acetylation of histone H4 lysine 16 (K16) and is highly ...
Regulation of chromatin structure involves histone modifications such as acetylation. Since 1996, t...
In human cells, histones bind DNA and form chromatin, a nucleoprotein complex important for various ...
Self-renewal and differentiation of hematopoietic stem cells (HSCs) are orchestrated by the combinat...
MOZ (also known as KAT6A and MYST3) is a histone acetyltransferase that is implicated in the develop...
© 2012 Dr. Bilal SheikhChromatin plays an integral role in regulating stem cells and embryonic devel...
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently...
Although histone acetylation is critical for maintaining embryonic stem cell pluripotency, the molec...
SummaryPluripotent embryonic stem cells (ESCs) maintain self-renewal and the potential for rapid res...
The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripoten...
MOF was first identified in <i>Drosophila melanogaster</i> as an important component of the dosage c...
The mammalian ortholog of the Drosophila MOF (males absent on the first) gene product is a histone H...
AbstractThe histone acetyltransferase Myst2 plays an important role in embryogenesis, but its functi...
Males absent on the first (MOF), also known as hMOF, MYST1, or KAT8, is a lysine acetyltransferase r...
Changes in chromatin structure and heritably regulating the gene expression by epigenetic mechanisms...
MOF (MYST1) is the major enzyme to catalyze acetylation of histone H4 lysine 16 (K16) and is highly ...
Regulation of chromatin structure involves histone modifications such as acetylation. Since 1996, t...
In human cells, histones bind DNA and form chromatin, a nucleoprotein complex important for various ...
Self-renewal and differentiation of hematopoietic stem cells (HSCs) are orchestrated by the combinat...
MOZ (also known as KAT6A and MYST3) is a histone acetyltransferase that is implicated in the develop...
© 2012 Dr. Bilal SheikhChromatin plays an integral role in regulating stem cells and embryonic devel...
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently...
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