Will the seven-helix bundle be a common structure for integral membrane proteins?

AbstractA prediction algorithm, designed to detect lipid-embedded helical regions in membrane proteins, was applied to the amino acid sequence of a chloroplast thylakoid membrane protein important in photosynthesis. It is suggested that the thylakoid membrane protein consists of 7 transmembrane helices connected by exposed turn segments, similar to current models for bacteriorhodopsin and bovine rhodopsin. This basic structural feature, the 7-helical bundle, may prove to be shared by many integral membrane proteins