Until recently, transcription could only be observed by measuring mRNA production of cell populations, thus obscuring the kinetics at the level of individual transcription events. A new study now shows that eukaryotic transcription, visualised in individual living cells, occurs in bursts — much as it does in prokaryotes
<div><p>Abstract</p><p>Deciphering how the regulatory DNA sequence of a gene dictates its expression...
Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra a...
The phenotypic characteristics of living organisms are shaped by the interactions of the genotype wi...
SummaryIt has not been possible to view the transcriptional activity of a single gene within a livin...
In prokaryotes and eukaryotes, most genes appear to be transcribed during short periods called trans...
It has not been possible to view the transcriptional activity of a single gene within a living eukar...
SummaryProtein levels have been shown to vary substantially between individual cells in clonal popul...
Transcription of genes can be discontinuous, occurring in pulses or bursts. It is not clear how prop...
In both prokaryotes and eukaryotes, transcription has been described as being temporally discontinuo...
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic tran...
With a developing appreciation of how noisy gene expression can be, and difficulties in deciphering ...
Eukaryotic transcription is a dynamic process relying on a large number of proteins. By measuring th...
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic tran...
Transcription of protein-encoding genes in eukaryotic cells is a dynamically coordinated process. Ma...
The information that instructs cells on how to create the molecules that perform cellular functions ...
<div><p>Abstract</p><p>Deciphering how the regulatory DNA sequence of a gene dictates its expression...
Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra a...
The phenotypic characteristics of living organisms are shaped by the interactions of the genotype wi...
SummaryIt has not been possible to view the transcriptional activity of a single gene within a livin...
In prokaryotes and eukaryotes, most genes appear to be transcribed during short periods called trans...
It has not been possible to view the transcriptional activity of a single gene within a living eukar...
SummaryProtein levels have been shown to vary substantially between individual cells in clonal popul...
Transcription of genes can be discontinuous, occurring in pulses or bursts. It is not clear how prop...
In both prokaryotes and eukaryotes, transcription has been described as being temporally discontinuo...
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic tran...
With a developing appreciation of how noisy gene expression can be, and difficulties in deciphering ...
Eukaryotic transcription is a dynamic process relying on a large number of proteins. By measuring th...
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic tran...
Transcription of protein-encoding genes in eukaryotic cells is a dynamically coordinated process. Ma...
The information that instructs cells on how to create the molecules that perform cellular functions ...
<div><p>Abstract</p><p>Deciphering how the regulatory DNA sequence of a gene dictates its expression...
Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra a...
The phenotypic characteristics of living organisms are shaped by the interactions of the genotype wi...
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