Outcomes of resection of giant hepatocellular carcinoma in a tertiary institution: does size matter?
- Thng, Yongxian
- Tan, Jarrod K.H.
- Shridhar, Iyer G.
- Chang, Stephen K.Y.
- Madhavan, Krishnakumar
- Kow, Alfred W.C.
DOIAbstract
AbstractBackgroundThe surgical management of giant hepatocellular carcinoma (G‐HCC), or HCC of ≥10 cm in diameter, remains controversial. The aim of this study was to compare the outcomes of surgical resection of, respectively, G‐HCC and small HCC (S‐HCC), or HCC measuring <10 cm.MethodsA retrospective review of all patients (n= 86) diagnosed with HCC and submitted to resection in a tertiary hospital during the period from January 2007 to June 2012 was conducted. Overall survival (OS), recurrence rates and perioperative mortality at 30 days were compared between patients with, respectively, G‐HCC and S‐HCC. Prognostic factors for OS were analysed.ResultsThe sample included 23 patients with G‐HCC (26.7%) and 63 with S‐HCC (73.3%) based on hi...
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