TRIB1, a homolog of Drosophila Tribbles, regulates the stability of transcription factors through physical interaction with the ubiquitin E3 ligase COP1. In this issue of Structure, Murphy et al. (2015) report the first X-ray analysis of the TRIB1 pseudokinase domain and its C-terminal COP1-binding extension
In 2000, investigators discovered Tribbles, a Drosophila protein that coordinates morphogenesis by i...
Review on TRIB1, with data on DNA, on the protein encoded, and where the gene is implicated
The mammalian tribble (TRIB) pseudokinase family has three homologues, which act as an adaptor prote...
TRIB1, a homolog of Drosophila Tribbles, regulates the stability of transcription factors through ph...
Title from PDF of title page viewed August 31, 2020Dissertation advisors: Leonard L. Dobens and Saul...
Pseudokinases are members of the protein kinase superfamily that are predicted to be catalytically i...
SummaryCCAAT-enhancer binding proteins (C/EBPs) are transcription factors that play a central role i...
COP1 is a highly conserved ubiquitin ligase that regulates diverse cellular processes in plants and ...
Tribbles proteins (TRIB1–3) are pseudokinases that recruit substrates to the COP1 ubiquitin ligase. ...
Sensing and interpreting extracellular signals in response to changes in the environment has been a ...
Constitutive photomorphogenic 1 (COP1) is a ubiquitin E3 ligase that has been implicated in developm...
The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved un...
Advances in the understanding of the Tribbles family of pseudokinases (TRIB1, TRIB2 and TRIB3) revea...
This commentary integrates historical and modern findings that underpin our understanding of the cel...
Tribbles homolog 2 (TRIB2) is a member of the mammalian Tribbles family of serine/threonine pseudoki...
In 2000, investigators discovered Tribbles, a Drosophila protein that coordinates morphogenesis by i...
Review on TRIB1, with data on DNA, on the protein encoded, and where the gene is implicated
The mammalian tribble (TRIB) pseudokinase family has three homologues, which act as an adaptor prote...
TRIB1, a homolog of Drosophila Tribbles, regulates the stability of transcription factors through ph...
Title from PDF of title page viewed August 31, 2020Dissertation advisors: Leonard L. Dobens and Saul...
Pseudokinases are members of the protein kinase superfamily that are predicted to be catalytically i...
SummaryCCAAT-enhancer binding proteins (C/EBPs) are transcription factors that play a central role i...
COP1 is a highly conserved ubiquitin ligase that regulates diverse cellular processes in plants and ...
Tribbles proteins (TRIB1–3) are pseudokinases that recruit substrates to the COP1 ubiquitin ligase. ...
Sensing and interpreting extracellular signals in response to changes in the environment has been a ...
Constitutive photomorphogenic 1 (COP1) is a ubiquitin E3 ligase that has been implicated in developm...
The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved un...
Advances in the understanding of the Tribbles family of pseudokinases (TRIB1, TRIB2 and TRIB3) revea...
This commentary integrates historical and modern findings that underpin our understanding of the cel...
Tribbles homolog 2 (TRIB2) is a member of the mammalian Tribbles family of serine/threonine pseudoki...
In 2000, investigators discovered Tribbles, a Drosophila protein that coordinates morphogenesis by i...
Review on TRIB1, with data on DNA, on the protein encoded, and where the gene is implicated
The mammalian tribble (TRIB) pseudokinase family has three homologues, which act as an adaptor prote...