AbstractDefective øX174 H protein-mediated DNA piloting indirectly influences the entire viral lifecycle. Faulty piloting can mask the H protein's other functions or inefficient penetration may be used to explain defects in post-piloting phenomena. For example, optimal synthesis of other viral proteins requires de novo H protein biosynthesis. As low protein concentrations affect morphogenesis, protein H's assembly functions remain obscure. An H protein mutant was isolated that allowed morphogenetic effects to be characterized independent of its other functions. The mutant protein aggregates assembly intermediates. Although excess internal scaffolding protein restores capsid assembly, the resulting mutant H protein-containing particles are l...
Recently we demonstrated that the co-expressed coronavirus membrane proteins have the capacity to as...
In order to initiate an infection, bacteriophages must deliver their large, hydrophilic genomes acro...
Recent genetic studies suggested that viral nonstructural (NS) proteins play important roles in morp...
AbstractDefective øX174 H protein-mediated DNA piloting indirectly influences the entire viral lifec...
The X174 DNA pilot protein H contains four predicted C-terminal coiled-coil domains. The region of t...
with an assembly pathway mediated by two scaffolding proteins. The external scaffolding protein D pl...
fX174 utilizes two scaffolding proteins during morphogenesis, an internal protein (B) and an externa...
AbstractThe first α-helices of Microviridae external scaffolding proteins function as coat protein s...
In the X174 procapsid crystal structure, 240 external scaffolding protein D subunits form 60 pairs o...
Scaffolding proteins are transiently associated with morphogenetic intermediates but are not found i...
Throughout recent history scientists have struggled to elucidate the biochemical and biophysical mec...
Many Mendelian monogenic disorders are caused by loss of the function of a single protein. This can ...
<p>After proteolytic cleavage of the full-length mutant htt protein, free monomeric N-terminal fragm...
Retroviral capsid (CA) proteins contain a uniquely conserved stretch of 20 amino acids which has bee...
The assembly of viral proteins and nucleic acids into mature and biologically active virions involve...
Recently we demonstrated that the co-expressed coronavirus membrane proteins have the capacity to as...
In order to initiate an infection, bacteriophages must deliver their large, hydrophilic genomes acro...
Recent genetic studies suggested that viral nonstructural (NS) proteins play important roles in morp...
AbstractDefective øX174 H protein-mediated DNA piloting indirectly influences the entire viral lifec...
The X174 DNA pilot protein H contains four predicted C-terminal coiled-coil domains. The region of t...
with an assembly pathway mediated by two scaffolding proteins. The external scaffolding protein D pl...
fX174 utilizes two scaffolding proteins during morphogenesis, an internal protein (B) and an externa...
AbstractThe first α-helices of Microviridae external scaffolding proteins function as coat protein s...
In the X174 procapsid crystal structure, 240 external scaffolding protein D subunits form 60 pairs o...
Scaffolding proteins are transiently associated with morphogenetic intermediates but are not found i...
Throughout recent history scientists have struggled to elucidate the biochemical and biophysical mec...
Many Mendelian monogenic disorders are caused by loss of the function of a single protein. This can ...
<p>After proteolytic cleavage of the full-length mutant htt protein, free monomeric N-terminal fragm...
Retroviral capsid (CA) proteins contain a uniquely conserved stretch of 20 amino acids which has bee...
The assembly of viral proteins and nucleic acids into mature and biologically active virions involve...
Recently we demonstrated that the co-expressed coronavirus membrane proteins have the capacity to as...
In order to initiate an infection, bacteriophages must deliver their large, hydrophilic genomes acro...
Recent genetic studies suggested that viral nonstructural (NS) proteins play important roles in morp...