Exercise leads to changes in muscle phenotype with important implications for exercise performance and health. A recent paper in Cell by Narkar et al. (2008) shows that many of the adaptations in muscle phenotype elicited by exercise can be mimicked by genetic manipulation and drug treatment in mice
Exercise mimetics are pharmacological compounds that trigger pathways similar to those activated as ...
Physical activity promotes metabolic and cardiovascular health benefits that derive in part from the...
Cachexia is a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass, with or wi...
Exercise exerts significant effects on the prevention and treatment of many diseases. However, even ...
Skeletal muscle has long been known as the target of several growth factors and hormones, including ...
The abundant health benefits of physical exercise are not being translated into practice. In an effo...
The past decade has witnessed growing scientific and commercial interest in the identification of bi...
<p>Cross sectional area (A), intersticium (B), percentage of type I muscle fibers (C), blood creatin...
The epidemic emergence of modern chronic diseases largely stems from the adoption of a sedentary lif...
Exercise leads to changes in muscle phenotype with important implications for exercise performance a...
Recent investigations from our lab have characterised the genome-wide epigenetic (DNA methylation) a...
Over the previous decade, there has been growing and fervent interest in scientific and commercial c...
<p>Muscular protein expression of AMPKα (A), p-AMPKα(Thr172) (B), p-ACC/ACC ratio (C), PPARδ (D), My...
Obesity and type 2 diabetes are associated disorders that involve a multiplicity of tissues. Both fa...
<p>Grip force (A), time until fall in the Rotarod evaluation (B) and time until exhaustion in the tr...
Exercise mimetics are pharmacological compounds that trigger pathways similar to those activated as ...
Physical activity promotes metabolic and cardiovascular health benefits that derive in part from the...
Cachexia is a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass, with or wi...
Exercise exerts significant effects on the prevention and treatment of many diseases. However, even ...
Skeletal muscle has long been known as the target of several growth factors and hormones, including ...
The abundant health benefits of physical exercise are not being translated into practice. In an effo...
The past decade has witnessed growing scientific and commercial interest in the identification of bi...
<p>Cross sectional area (A), intersticium (B), percentage of type I muscle fibers (C), blood creatin...
The epidemic emergence of modern chronic diseases largely stems from the adoption of a sedentary lif...
Exercise leads to changes in muscle phenotype with important implications for exercise performance a...
Recent investigations from our lab have characterised the genome-wide epigenetic (DNA methylation) a...
Over the previous decade, there has been growing and fervent interest in scientific and commercial c...
<p>Muscular protein expression of AMPKα (A), p-AMPKα(Thr172) (B), p-ACC/ACC ratio (C), PPARδ (D), My...
Obesity and type 2 diabetes are associated disorders that involve a multiplicity of tissues. Both fa...
<p>Grip force (A), time until fall in the Rotarod evaluation (B) and time until exhaustion in the tr...
Exercise mimetics are pharmacological compounds that trigger pathways similar to those activated as ...
Physical activity promotes metabolic and cardiovascular health benefits that derive in part from the...
Cachexia is a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass, with or wi...
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