Oxidative stress in chronic obstructive pulmonary disease patients submitted to a rehabilitation program
- Pinho, R.A.
- Chiesa, D.
- Mezzomo, K.M.
- Andrades, M.E.
- Bonatto, F.
- Gelain, D.
- Dal Pizzol, F.
- Knorst, M.M.
- Moreira, J.C.F.
DOIAbstract
SummaryPulmonary rehabilitation (PR) improves physical capacity and health quality in patients with chronic obstructive pulmonary disease (COPD). However, the effect of exercise on oxidative stress markers in COPD patients is only partially known. This study was designed to evaluate the oxidative stress response to long-term exercise in patients with COPD enrolled in a PR program. Fifteen COPD patients (FEV1<60%), age between 50 and 60 years, ex-smokers, were separated in two groups: exercise-trained (n=8) and sedentary group (n=7). Exercise consisted of an 8-week conditioning program using a cycle ergometer (three times a week, 1h session). An endurance test (60% of maximal load in an incremental cycle test) was performed before and after ...
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