Unc93B1, a multitransmembrane ER-resident protein, controls intracellular trafficking of endosomal Toll-like receptors. In this issue of Immunity, Fukui et al. (2011) revealed that Unc93B1 regulates differential transport of TLR7 and TLR9 into signaling endosomes to prevent autoimmunity
Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartmen...
UNC93B1 associates with Toll-Like Receptor (TLR) 3, 7 and 9, mediating their translocation from the ...
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traff...
UNC93B1, a multipass transmembrane protein required for TLR3, TLR7, TLR9, TLR11, TLR12, and TLR13 fu...
SummaryToll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been ...
Signalling by means of toll- like receptors ( TLRs) is essential for the development of innate and a...
Unc-93 homolog B1 (UNC93B1) is a key regulator of nucleic acid (NA)-sensing Toll-like receptors (TLR...
Sensing of nucleic acids by TLRs is crucial in the host defense against viruses and bacteria. Unc-93...
Toll-like receptors (TLRs) sense the presence of microbial and viral pathogens by signal transductio...
Nucleic acid-sensing Toll-like receptors (TLRs) are subject to complex regulation to facilitate the ...
Toll-like receptors (TLRs) 3, 7, 8, and 9 are localized to intracellular compartments where they enc...
At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA a...
The proper trafficking and localization of Toll-like receptors (TLRs) are important for specific lig...
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traff...
Toll-like receptors (TLRs) represent the innate immune system's first line of defense against invadi...
Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartmen...
UNC93B1 associates with Toll-Like Receptor (TLR) 3, 7 and 9, mediating their translocation from the ...
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traff...
UNC93B1, a multipass transmembrane protein required for TLR3, TLR7, TLR9, TLR11, TLR12, and TLR13 fu...
SummaryToll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been ...
Signalling by means of toll- like receptors ( TLRs) is essential for the development of innate and a...
Unc-93 homolog B1 (UNC93B1) is a key regulator of nucleic acid (NA)-sensing Toll-like receptors (TLR...
Sensing of nucleic acids by TLRs is crucial in the host defense against viruses and bacteria. Unc-93...
Toll-like receptors (TLRs) sense the presence of microbial and viral pathogens by signal transductio...
Nucleic acid-sensing Toll-like receptors (TLRs) are subject to complex regulation to facilitate the ...
Toll-like receptors (TLRs) 3, 7, 8, and 9 are localized to intracellular compartments where they enc...
At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA a...
The proper trafficking and localization of Toll-like receptors (TLRs) are important for specific lig...
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traff...
Toll-like receptors (TLRs) represent the innate immune system's first line of defense against invadi...
Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartmen...
UNC93B1 associates with Toll-Like Receptor (TLR) 3, 7 and 9, mediating their translocation from the ...
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traff...
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