AbstractThe tetrahydrobiopterin-dependent iron-enzyme tyrosine hydroxylase (TH) catalyses the rate-limiting step in catecholamine biosynthesis. Electron paramagnetic resonance (EPR) data show that following phosphorylation of Ser-40 by protein kinase A, the enzyme-bound Fe(III), coordinated to catecholamines, can be reduced by 6-methyl-tetrahydropterin under turnover conditions. The 8-fold increase in product formation upon phosphorylation can partly be explained by an increase in the fraction of active TH, by dissociation of the endogenous catecholamine inhibitors
The [4Fe–4S] protein IspH in the methylerythritol phosphate isoprenoid biosynthesis pathway is an im...
Tyrosine Hydroxylase (TyrH) is a pterin-dependent mononuclear non-heme iron oxygenase. TyrH catalyz...
Electron paramagnetic resonance (EPR) spectroscopy is a powerful tool for obtaining structural infor...
AbstractThe tetrahydrobiopterin-dependent iron-enzyme tyrosine hydroxylase (TH) catalyses the rate-l...
AbstractBovine adrenal tyrosine hydroxylase (TH) is isolated in a partially inhibited state with the...
Tyrosine hydroxylase is a nonheme iron enzyme found in the nervous system that catalyzes the hydroxy...
The rate-limiting enzyme in catecholamine synthesis is tyrosine hydroxylase. It is phosphorylated at...
Tyrosine hydroxylase is a mononuclear non-heme iron monooxygenase found in the central nervous syste...
Isoforms (1 -4) of human tyrosine hydroxylase (TH) have been expressed in Escherichia coli and purif...
Tyrosine hydroxylase (TH) performs the first and rate-limiting step in the synthesis of catecholamin...
Research Doctorate - Doctor of Philosopy (PhD)Tyrosine hydroxylase (TH), the rate-limiting enzyme in...
Tyrosine hydroxylase (TyrH) catalyzes the pterin-dependent hydroxylation of tyrosine to form dihydr...
Tyrosine hydroxylase (TH), the rate-limiting enzyme in the biosynthesis of the catecholamines dopami...
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine synthesis. Its activity is kn...
N-methyl-norsalsolinol and related tetrahydroisoquinolines accumulate in the nigrostriatal system of...
The [4Fe–4S] protein IspH in the methylerythritol phosphate isoprenoid biosynthesis pathway is an im...
Tyrosine Hydroxylase (TyrH) is a pterin-dependent mononuclear non-heme iron oxygenase. TyrH catalyz...
Electron paramagnetic resonance (EPR) spectroscopy is a powerful tool for obtaining structural infor...
AbstractThe tetrahydrobiopterin-dependent iron-enzyme tyrosine hydroxylase (TH) catalyses the rate-l...
AbstractBovine adrenal tyrosine hydroxylase (TH) is isolated in a partially inhibited state with the...
Tyrosine hydroxylase is a nonheme iron enzyme found in the nervous system that catalyzes the hydroxy...
The rate-limiting enzyme in catecholamine synthesis is tyrosine hydroxylase. It is phosphorylated at...
Tyrosine hydroxylase is a mononuclear non-heme iron monooxygenase found in the central nervous syste...
Isoforms (1 -4) of human tyrosine hydroxylase (TH) have been expressed in Escherichia coli and purif...
Tyrosine hydroxylase (TH) performs the first and rate-limiting step in the synthesis of catecholamin...
Research Doctorate - Doctor of Philosopy (PhD)Tyrosine hydroxylase (TH), the rate-limiting enzyme in...
Tyrosine hydroxylase (TyrH) catalyzes the pterin-dependent hydroxylation of tyrosine to form dihydr...
Tyrosine hydroxylase (TH), the rate-limiting enzyme in the biosynthesis of the catecholamines dopami...
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine synthesis. Its activity is kn...
N-methyl-norsalsolinol and related tetrahydroisoquinolines accumulate in the nigrostriatal system of...
The [4Fe–4S] protein IspH in the methylerythritol phosphate isoprenoid biosynthesis pathway is an im...
Tyrosine Hydroxylase (TyrH) is a pterin-dependent mononuclear non-heme iron oxygenase. TyrH catalyz...
Electron paramagnetic resonance (EPR) spectroscopy is a powerful tool for obtaining structural infor...