Target validation of cytochrome P450 CYP1B1 in prostate carcinoma with protein expression in associated hyperplastic and premalignant tissue
- Carnell, Dawn M.
- Smith, Rowena E.
- Daley, Frances M.
- Barber, Paul R.
- Hoskin, Peter J.
- Wilson, George D.
- Murray, Graeme I.
- Everett, Steven A.
Publication date
February 2004
DOIAbstract
To investigate the localization and distribution of cytochrome P450 CYP1B1 protein expression in patients diagnosed with prostate carcinoma compared to those with bladder carcinoma. To validate CYP1B1 as a molecular target for the development of selective cancer therapeutics for use in combination with radiation
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