AbstractA strikingly large number of mitochondrial DNA (mtDNA) mutations have been found to be the cause of respiratory chain and oxidative phosphorylation defects. These mitochondrial disorders were the first to be investigated after the small mtDNA had been sequenced in the 80s. Only recently numerous diseases resulting from mutations in nuclear genes encoding mitochondrial proteins have been characterized. Among these, nine are caused by defects of mitochondrial carriers, a family of nuclear-coded proteins that shuttle a variety of metabolites across the mitochondrial membrane. Mutations of mitochondrial carrier genes involved in mitochondrial functions other than oxidative phosphorylation are responsible for carnitine/acylcarnitine carr...
AbstractMitochondrial disorders are a group of clinically heterogeneous diseases, commonly defined b...
A large group of mitochondrial disorders, ranging from early-onset pediatric encephalopathic syndrom...
AbstractMitochondrial disorders have the highest incidence among congenital metabolic diseases, and ...
AbstractA strikingly large number of mitochondrial DNA (mtDNA) mutations have been found to be the c...
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting fro...
Since the end of nineties numerous mitochondrial diseases have been found to be related to mutations...
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting fro...
Mitochondrial diseases involve the respiratory chain, which is under the dual control of nuclear and...
The concept of a mitochondrial disorder was initially described in 1962, in a patient with altered e...
Mitochondrial disorders are caused by mutations in either nuclear or mitochondrial genes involved in...
AbstractBy convention, the term “mitochondrial diseases” refers to disorders of the mitochondrial re...
Mitochondrial disorders are caused by deficient respiratory chain function, resulting in a complex s...
Mitochondria contain respiratory chain enzyme complexes that carry out oxidative phosphorylation and...
Mitochondria are organelles responsible for production of mostenergy through oxidative phosphorylati...
The mitochondrial myopathies or encephalomyopathies with known biochemical defects can be divided in...
AbstractMitochondrial disorders are a group of clinically heterogeneous diseases, commonly defined b...
A large group of mitochondrial disorders, ranging from early-onset pediatric encephalopathic syndrom...
AbstractMitochondrial disorders have the highest incidence among congenital metabolic diseases, and ...
AbstractA strikingly large number of mitochondrial DNA (mtDNA) mutations have been found to be the c...
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting fro...
Since the end of nineties numerous mitochondrial diseases have been found to be related to mutations...
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting fro...
Mitochondrial diseases involve the respiratory chain, which is under the dual control of nuclear and...
The concept of a mitochondrial disorder was initially described in 1962, in a patient with altered e...
Mitochondrial disorders are caused by mutations in either nuclear or mitochondrial genes involved in...
AbstractBy convention, the term “mitochondrial diseases” refers to disorders of the mitochondrial re...
Mitochondrial disorders are caused by deficient respiratory chain function, resulting in a complex s...
Mitochondria contain respiratory chain enzyme complexes that carry out oxidative phosphorylation and...
Mitochondria are organelles responsible for production of mostenergy through oxidative phosphorylati...
The mitochondrial myopathies or encephalomyopathies with known biochemical defects can be divided in...
AbstractMitochondrial disorders are a group of clinically heterogeneous diseases, commonly defined b...
A large group of mitochondrial disorders, ranging from early-onset pediatric encephalopathic syndrom...
AbstractMitochondrial disorders have the highest incidence among congenital metabolic diseases, and ...