The vertebrate segmentation clock is a molecular oscillator that regulates the periodicity of somite formation. Three signalling pathways have been proposed to underlie the molecular mechanism of the oscillator, namely the Notch, Wnt and Fgf pathways. Characterizing the roles and hierarchy of these three pathways in the oscillator mechanism is currently the focus of intense research. Recent publications report the first identification of a molecular mechanism involved in the regulation of the pace of this oscillator. We review these and other recent findings regarding the interaction between the three pathways in the oscillator mechanism that have significantly expanded our understanding of the segmentation clock
Coupled biological oscillators can tick with the same period. How this collective period is establis...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequenti...
The vertebrate segmentation clock is a molecular oscillator that regulates the periodicity of somite...
The vertebral column is derived from somites formed by segmentation of presomitic mesoderm, a fundam...
In the last few years, the efforts to elucidate the mechanisms underlying the segmentation clock in ...
AbstractThe periodic formation of somites during vertebrate segmentation has been suggested to invol...
AbstractVertebrate segmentation is manifested during embryonic development as serially repeated unit...
The Segmentation clock is a population of cellular genetic oscillators, located in the posterior of ...
AbstractThe vertebral column derives from somites generated by segmentation of presomitic mesoderm (...
The segmental organization of the vertebral column is established early in embryogenesis, when pairs...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
During somitogenesis an oscillatory mechanism termed the “segmentation” clock generates periodic wav...
The vertebral column is derived from somites formed by segmentation of presomitic mesoderm, a fundam...
Coupled biological oscillators can tick with the same period. How this collective period is establis...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequenti...
The vertebrate segmentation clock is a molecular oscillator that regulates the periodicity of somite...
The vertebral column is derived from somites formed by segmentation of presomitic mesoderm, a fundam...
In the last few years, the efforts to elucidate the mechanisms underlying the segmentation clock in ...
AbstractThe periodic formation of somites during vertebrate segmentation has been suggested to invol...
AbstractVertebrate segmentation is manifested during embryonic development as serially repeated unit...
The Segmentation clock is a population of cellular genetic oscillators, located in the posterior of ...
AbstractThe vertebral column derives from somites generated by segmentation of presomitic mesoderm (...
The segmental organization of the vertebral column is established early in embryogenesis, when pairs...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
During somitogenesis an oscillatory mechanism termed the “segmentation” clock generates periodic wav...
The vertebral column is derived from somites formed by segmentation of presomitic mesoderm, a fundam...
Coupled biological oscillators can tick with the same period. How this collective period is establis...
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). So...
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequenti...