Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention

AbstractObjectivesThe purpose of this study was to determine the clinical and angiographic correlates and outcomes of patients with suboptimal coronary flow after primary percutaneous coronary interventions (PCI).BackgroundThe clinical and angiographic correlates and outcomes of Thrombolysis in Myocardial Infarction (TIMI) ≤2 flow in patients treated with primary PCI are not known.MethodsWe evaluated 3,362 patients with ST elevation myocardial infarction enrolled in various Primary Angioplasty in Myocardial Infarction trials, who underwent primary PCI.ResultsPost-procedural final TIMI ≤2 flow occurred in 232 (6.9%) patients. Multivariate analysis identified age ≥70 years (odds ratio [OR], 1.6; 95% confidence interval [CI], 1.1 to 2.2), diabetes (OR 1.9; 95% CI, 1.3 to 2.7), symptom onset to emergency room presentation (OR 1.1; 95% CI, 1.1 to 1.2); initial TIMI ≤1 flow (OR 3.2; 95% CI, 1.9 to 5.5), and left ventricular ejection fraction