In this issue, Xiao et al. challenge the notion that cold temperatures promote longevity solely through thermodynamic effects. They show that low temperatures activate a cold-sensitive cation channel, TRPA-1, which triggers a complex signaling pathway in both neurons and nonneuronal cells to extend the lifespan of Caenorhabditis elegans
Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorh...
The biological process of aging is the primary determinant of lifespan, but the factors that influen...
Temperature potently modulates various physiologic processes including organismal motility, growth r...
In this issue, Xiao et al. challenge the notion that cold temperatures promote longevity solely thro...
SummaryBoth poikilotherms and homeotherms live longer at lower body temperatures, highlighting a gen...
Traditional model suggested that low temperature promote longevity simply by a purely passive thermo...
SummaryBackgroundMany ectotherms, including C. elegans, have shorter life spans at high temperature ...
SummaryFor ectotherms, lifespan is increased at low temperature and decreased at high temperature. A...
Temperature-sensing neurons in C. elegans reduce the life-shortening effects of high temperatures vi...
Temperature profoundly affects aging in both poikilotherms and homeotherms. A general belief is that...
SummaryTemperature profoundly affects aging in both poikilotherms and homeotherms. A general belief ...
Sensory perception, including thermosensation, shapes longevity in diverse organisms, but longevity-...
A moderate reduction in body temperature can induce a remarkable lifespan extension. Here we examine...
Animals are often not growing at the maximum rate, but can compensate for a bad start of life by fur...
Animals are often not growing at the maximum rate, but can compensate for a bad start of life by sub...
Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorh...
The biological process of aging is the primary determinant of lifespan, but the factors that influen...
Temperature potently modulates various physiologic processes including organismal motility, growth r...
In this issue, Xiao et al. challenge the notion that cold temperatures promote longevity solely thro...
SummaryBoth poikilotherms and homeotherms live longer at lower body temperatures, highlighting a gen...
Traditional model suggested that low temperature promote longevity simply by a purely passive thermo...
SummaryBackgroundMany ectotherms, including C. elegans, have shorter life spans at high temperature ...
SummaryFor ectotherms, lifespan is increased at low temperature and decreased at high temperature. A...
Temperature-sensing neurons in C. elegans reduce the life-shortening effects of high temperatures vi...
Temperature profoundly affects aging in both poikilotherms and homeotherms. A general belief is that...
SummaryTemperature profoundly affects aging in both poikilotherms and homeotherms. A general belief ...
Sensory perception, including thermosensation, shapes longevity in diverse organisms, but longevity-...
A moderate reduction in body temperature can induce a remarkable lifespan extension. Here we examine...
Animals are often not growing at the maximum rate, but can compensate for a bad start of life by fur...
Animals are often not growing at the maximum rate, but can compensate for a bad start of life by sub...
Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorh...
The biological process of aging is the primary determinant of lifespan, but the factors that influen...
Temperature potently modulates various physiologic processes including organismal motility, growth r...