The MAVS protein plays a critical role in the assembly of an antiviral signaling complex on mitochondrial membranes. Hou et al. (2011) now report that virus infection induces a conformational change in MAVS, leading to the prion-like formation of functional self-aggregates that provide a sensitive trigger for antiviral signaling
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mit...
SummaryViral infection triggers host innate immune responses through activation of the transcription...
BACKGROUND: Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and ...
The MAVS protein plays a critical role in the assembly of an antiviral signaling complex on mitochon...
The mitochondrial antiviral signaling (MAVS) adaptor protein is a central signaling hub required for...
The mitochondrial antiviral signaling (MAVS) adaptor protein is a central signaling hub required for...
SummaryIn response to viral infection, RIG-I-like RNA helicases bind to viral RNA and activate the m...
To defend cells against viruses, the MAVS (mitochondrial antiviral signaling) adaptor protein initia...
SummaryIn response to viral infection, RIG-I-like RNA helicases bind to viral RNA and activate the m...
Mitochondrial antiviral signalling protein (MAVS) acts as a critical adaptor protein to transduce an...
The mitochondrial antiviral signaling (MAVS) protein plays a central role in innate antiviral immuni...
AbstractIn most eukaryotic cells, mitochondria have various essential roles for proper cell function...
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mit...
Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and triggers an ...
<div><p>RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the o...
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mit...
SummaryViral infection triggers host innate immune responses through activation of the transcription...
BACKGROUND: Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and ...
The MAVS protein plays a critical role in the assembly of an antiviral signaling complex on mitochon...
The mitochondrial antiviral signaling (MAVS) adaptor protein is a central signaling hub required for...
The mitochondrial antiviral signaling (MAVS) adaptor protein is a central signaling hub required for...
SummaryIn response to viral infection, RIG-I-like RNA helicases bind to viral RNA and activate the m...
To defend cells against viruses, the MAVS (mitochondrial antiviral signaling) adaptor protein initia...
SummaryIn response to viral infection, RIG-I-like RNA helicases bind to viral RNA and activate the m...
Mitochondrial antiviral signalling protein (MAVS) acts as a critical adaptor protein to transduce an...
The mitochondrial antiviral signaling (MAVS) protein plays a central role in innate antiviral immuni...
AbstractIn most eukaryotic cells, mitochondria have various essential roles for proper cell function...
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mit...
Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and triggers an ...
<div><p>RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the o...
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mit...
SummaryViral infection triggers host innate immune responses through activation of the transcription...
BACKGROUND: Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and ...
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