Six-Month Incidence and Persistence of Oral HPV Infection in HIV-Negative and HIV-Infected Men Who Have Sex with Men
- Mooij Sofie H.
- Boot Hein J.
- Speksnijder Arjen G. C. L.
- Meijer Chris J. L. M.
- King Audrey J.
- Verhagen Dominique W. M.
- de Vries Henry J. C.
- Quint Wim G. V.
- Molijn Anco
- de Koning Maurits N. C.
- van der Sande Marianne A. B.
- van der Loeff Maarten F. Schim
DOIAbstract
Our aim was to assess incidence and persistence of oral HPV infection in HIV-negative and HIV-infected men who have sex with men (MSM). sequencing to identify additional HPV types. Multivariable logistic regression analyses using generalized estimating equations (GEE) were performed to assess determinants for oral high-risk HPV incidence and persistence.<0.001). HIV infection and recent use of cannabis were both independently associated with high-risk HPV incidence. Persistent high-risk HPV was observed in 48/130 (36.9%) infections.Incidence of oral high-risk HPV infection in MSM is substantial, and is associated with HIV infection. Over a third of HPV infections persisted over a 6-month period
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