experiments. drug activity, including serial, non-invasive assessments in live mice, producing results which correlated closely with colony-forming unit (CFU) counts for a panel of drugs with various mechanisms of action. are exceptional tools for pre-clinical evaluation of new drugs to treat BU due to their potential to drastically reduce the time, effort, animals, compound, and costs required to evaluate drug activity
<p>Sets of three mice were used in each experiment. CFU counts of the inoculated strains from faecal...
<p>The mice were challenged with K7 at the dose of 2.5×10<sup>8</sup> cfu. At the indicated times, b...
<p>Representative plates from bacteriocin activity assay were shown for each treatment. ‘(+)’ repres...
experiments. drug activity, including serial, non-invasive assessments in live mice, producing resu...
assays to screen potential new drugs and existing compound libraries are essential. lower than that...
Laboratory testing is a prerequisite to predictions about the potential value of human clinical tria...
textabstractThe aim of the study is to compare counting of colony forming units (CFU), the time to p...
<p>Groups of five mice were infected with <i>T. cruzi</i> and treated with different compounds follo...
A large variety of mouse models for human skin and adnexa diseases are readily available from invest...
A large variety of mouse models for human skin, hair, and nail diseases are readily available from i...
Murine tuberculosis drug efficacy studies have historically monitored bacterial burden based on CFU ...
infection in BALB/c mice. infection was examined in mouse model by enumerating residual fungal burd...
According to European Union directive 2010/63/EU a severity classification of experimental procedure...
<p>Groups of mice were infected i.n. (A, B, and C) or i.d. (D, E, and F) with wild-type Schu S4 (50 ...
In vivo reporter gene and imaging technologies have the potential to contribute to the drug discover...
<p>Sets of three mice were used in each experiment. CFU counts of the inoculated strains from faecal...
<p>The mice were challenged with K7 at the dose of 2.5×10<sup>8</sup> cfu. At the indicated times, b...
<p>Representative plates from bacteriocin activity assay were shown for each treatment. ‘(+)’ repres...
experiments. drug activity, including serial, non-invasive assessments in live mice, producing resu...
assays to screen potential new drugs and existing compound libraries are essential. lower than that...
Laboratory testing is a prerequisite to predictions about the potential value of human clinical tria...
textabstractThe aim of the study is to compare counting of colony forming units (CFU), the time to p...
<p>Groups of five mice were infected with <i>T. cruzi</i> and treated with different compounds follo...
A large variety of mouse models for human skin and adnexa diseases are readily available from invest...
A large variety of mouse models for human skin, hair, and nail diseases are readily available from i...
Murine tuberculosis drug efficacy studies have historically monitored bacterial burden based on CFU ...
infection in BALB/c mice. infection was examined in mouse model by enumerating residual fungal burd...
According to European Union directive 2010/63/EU a severity classification of experimental procedure...
<p>Groups of mice were infected i.n. (A, B, and C) or i.d. (D, E, and F) with wild-type Schu S4 (50 ...
In vivo reporter gene and imaging technologies have the potential to contribute to the drug discover...
<p>Sets of three mice were used in each experiment. CFU counts of the inoculated strains from faecal...
<p>The mice were challenged with K7 at the dose of 2.5×10<sup>8</sup> cfu. At the indicated times, b...
<p>Representative plates from bacteriocin activity assay were shown for each treatment. ‘(+)’ repres...
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