The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) report the structure of the complex of DNA Damage-Binding Protein 1 (DDB1) and DDB2 bound to a DNA photodimer, providing critical insight into the repair of DNA damage caused by ultraviolet light
(DDB2). Although the function of DDB is unclear, mutation on DDB2 is associated with cellular sensit...
UV-DDB, a key protein in human global nucleotide excision repair (NER), binds avidly to abasic sites...
acids, 48 kDa; DDB1 (p127) and DDB2 (p48) form a stable heterodimer UV-DDB. Function The damage-spec...
The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) ...
SummaryUltraviolet (UV) light-induced pyrimidine photodimers are repaired by the nucleotide excision...
Nucleotide excision repair (NER) is a DNA repair pathway that processes helix distorting lesions in ...
How human DNA repair proteins survey the genome for UV-induced photoproducts remains a poorly unders...
Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for...
UV light-induced photoproducts are recognized and removed by the nucleotide-excision repair (NER) pa...
How tightly packed chromatin is thoroughly inspected for DNA damage is one of the fundamental unansw...
Damage-specific DNA binding protein 1 (DDB1) is a conserved protein component of the damaged DNA bin...
textabstractNucleotide excision repair (NER) is the principal pathway for counteracting cytotoxic an...
How tightly packed chromatin is thoroughly inspected for DNA damage is one of the fundamental unansw...
The work presented in this thesis aims to contribute to understanding of the molecular mechanisms th...
Nucleotide excision repair (NER) is the principal pathway for counteracting cytotoxic and mutagenic ...
(DDB2). Although the function of DDB is unclear, mutation on DDB2 is associated with cellular sensit...
UV-DDB, a key protein in human global nucleotide excision repair (NER), binds avidly to abasic sites...
acids, 48 kDa; DDB1 (p127) and DDB2 (p48) form a stable heterodimer UV-DDB. Function The damage-spec...
The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) ...
SummaryUltraviolet (UV) light-induced pyrimidine photodimers are repaired by the nucleotide excision...
Nucleotide excision repair (NER) is a DNA repair pathway that processes helix distorting lesions in ...
How human DNA repair proteins survey the genome for UV-induced photoproducts remains a poorly unders...
Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for...
UV light-induced photoproducts are recognized and removed by the nucleotide-excision repair (NER) pa...
How tightly packed chromatin is thoroughly inspected for DNA damage is one of the fundamental unansw...
Damage-specific DNA binding protein 1 (DDB1) is a conserved protein component of the damaged DNA bin...
textabstractNucleotide excision repair (NER) is the principal pathway for counteracting cytotoxic an...
How tightly packed chromatin is thoroughly inspected for DNA damage is one of the fundamental unansw...
The work presented in this thesis aims to contribute to understanding of the molecular mechanisms th...
Nucleotide excision repair (NER) is the principal pathway for counteracting cytotoxic and mutagenic ...
(DDB2). Although the function of DDB is unclear, mutation on DDB2 is associated with cellular sensit...
UV-DDB, a key protein in human global nucleotide excision repair (NER), binds avidly to abasic sites...
acids, 48 kDa; DDB1 (p127) and DDB2 (p48) form a stable heterodimer UV-DDB. Function The damage-spec...
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