Compounds
- Canavaci Adriana M. C.
- Bustamante Juan M.
- Padilla Angel M.
- Perez Brandan Cecilia M.
- Simpson Laura J.
- Xu Dan
- Boehlke Courtney L.
- Tarleton Rick L.
DOIAbstract
assays to screen potential new drugs and existing compound libraries are essential. lower than that of BZ., mice were infected in the footpads with fluorescent or bioluminescent parasites and the signal intensity was measured as a surrogate of parasite load at the site of infection before and after initiation of drug treatment. Importantly, the efficacy of various drugs as determined in this short-term (<2 weeks) assay mirrored that of a 40 day treatment course.
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