Chromatin-based repression is a major mechanism for epigenetically heritable variation. Work in the July 21 issue of Molecular Cell quantitatively examines transcriptional silencing in individual yeast cells, demonstrating locus-specific effects and finding that different silencing mutants exhibit qualitatively distinct single-cell defects
Gene silencing in budding yeast is mediated by Sir protein binding to unacetylated nucleosomes to fo...
SummaryClassic “position-effect” experiments repositioned genes near telomeres to demonstrate that t...
<div><p>Packaging of eukaryotic genomes into chromatin has wide-ranging effects on gene transcriptio...
Phenotypic diversity and fidelity can be balanced by controlling stochastic molecular mechanisms. Ep...
Eukaryotic cells package designated regions of their DNA into a condensed structure referred to as h...
Single-celled microbes have been the darlings of scientific study for many decades. The facility wit...
DNA in eukaryotic organisms is complexed with histone and non-histone proteins to form chromatin. Ge...
We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known ...
The establishment of silencing in Saccharomyces cerevisiae is similar to heterochromatin formation i...
The establishment of silencing in Saccharomyces cerevisiae is similar to heterochromatin formation i...
In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variatio...
In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variatio...
In eukaryotes, epigenetic events govern diverse processes, ranging from gene expression to other asp...
Packaging of eukaryotic genomes into chromatin has wide-ranging effects on gene transcription. Curio...
We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known ...
Gene silencing in budding yeast is mediated by Sir protein binding to unacetylated nucleosomes to fo...
SummaryClassic “position-effect” experiments repositioned genes near telomeres to demonstrate that t...
<div><p>Packaging of eukaryotic genomes into chromatin has wide-ranging effects on gene transcriptio...
Phenotypic diversity and fidelity can be balanced by controlling stochastic molecular mechanisms. Ep...
Eukaryotic cells package designated regions of their DNA into a condensed structure referred to as h...
Single-celled microbes have been the darlings of scientific study for many decades. The facility wit...
DNA in eukaryotic organisms is complexed with histone and non-histone proteins to form chromatin. Ge...
We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known ...
The establishment of silencing in Saccharomyces cerevisiae is similar to heterochromatin formation i...
The establishment of silencing in Saccharomyces cerevisiae is similar to heterochromatin formation i...
In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variatio...
In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variatio...
In eukaryotes, epigenetic events govern diverse processes, ranging from gene expression to other asp...
Packaging of eukaryotic genomes into chromatin has wide-ranging effects on gene transcription. Curio...
We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known ...
Gene silencing in budding yeast is mediated by Sir protein binding to unacetylated nucleosomes to fo...
SummaryClassic “position-effect” experiments repositioned genes near telomeres to demonstrate that t...
<div><p>Packaging of eukaryotic genomes into chromatin has wide-ranging effects on gene transcriptio...
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